吡喹酮、阿苯达唑剂量递增疗法治疗脑囊虫病415例疗效观察  

OBSERVATION ON TREATMENT OF 415 NEUROCYSTICERCOSIS CASES WITH PRAZIQ UANTEL AND ALBENDAZOLE ADMINISTERED ON INCREASING -DOSE REGIME

作　　者：李庆山[1] 葛凌云[1] 徐洪秀[1] 杨艳君[1] 张敬举[1] 王昌源[1] 孔庆安[1] 孔巧云[1] 于振华[1] 贾凤菊[1] 侯连泉[1] 孙广平[1] 马巧荣[1] 李怀菊[1] 

机构地区：[1]山东省寄生虫病防治研究所,山东囊虫病治疗中心

出　　处：《中国寄生虫病防治杂志》1995年第2期124-126,共3页Chinese Journal of Parasitic Disease Control

摘　　要：应用吡喹酮（ＰＱＴ）、阿苯达唑（ＡＬＢ）３种疗法治疗脑囊虫病４１５例：１．ＰＱＴ３０ｍｇ／ｋｇ·ｄ×１２，第２、３疗程为３０～５０ｍｇ／ｋｇ·ｄ×１２，疗程间隔２～３个月。２．ＰＱＴ１０ｍｇ／ｋｇ·ｄ×１２，递增至３０～５０ｍｇ／ｋｇ·ｄ×１２，疗程间隔２～３个月。３．ＡＬＢ、ＰＱＴ联合治疗，共３个疗程。总治愈率为８８．４３％，总有效率为９９．７６％。Satisfactory results were obtained on 415 cases with neurocysticercosis treatedwith praziquantel and albendazole. The theraputics used were:(1) praziquantel 30 mg/kg·d×12 and repeating the same course or increasing the dosage to 50 mg/kg·d×12 after 2-3monthsinterval;(2) praziquantel 10 mg/kg·d×12 and gradually increasing to 30-50 mg/kg·d×12with the course intervalof 2-3months;(3) praziquantel combined with albendazole. The totaldoses either of both drugs for each case was similar. The cure rate was 88. 43%and effectivenessrate 99. 76%. The treatment for reducing intracranial hypertension and anti-epilepsy wasadministered as well according to the intensity of reaction occurred during the anticysticercuscourses.

关 键 词：脑囊虫病 吡喹酮 阿苯达唑 治疗 

分 类 号：R532.330.5[医药卫生—内科学]