幽门螺旋菌感染危险因素的流行病学调查  

Epidemiology Investigation on Risk Factors of H. Pylori Infection

作　　者：程亦陵[1] 殷秋华 钟宏良[1] 

机构地区：[1]苏州医学院流行病学教研室

出　　处：《中国公共卫生学报》1995年第6期327-330,共4页

摘　　要：１９９４年２月２８日～４月２日间选择作胃内镜检查者９１例，年龄为２１～７３岁，其中男性５４例，女性３７例。以涂片镜检阳性作为诊断幽门螺旋菌（ＨＰ）感染的标准，对有关生活习惯、社会经济卫生情况等１３个变量进行多因素非条件Ｌｏｇｉｓｔｉｃ回归分析。结果表明：变量全部进入非条件Ｌｏｇｉｓｔｉｃ回归模型，用最大似然分析法作多因素逐步Ｌｏｇｉｔｉｃ回归分析，在分别平衡其余１２个变量的条件下，判定每个变量与ＨＰ镜检阳性相关性联系的意义，与单因素分析一样亦得出文化程度与家中是否饲养动物两变量的回归系数β值有显著性差异，结果未提示两者有交互作用。而感染情况与一般认为与胃炎有关的吸烟、饮酒、辛辣食物等生活习惯无关，提示它们很可能是互相独立的致病因素。这对进一步在一般人群中的深入研究具有一定的参考价值。Helicobacter pylon(H. pylori)is now accepted as the leading cause of active chronic antral gastritis in man,and also has relationship with peptic ulcer and gastric cancer. There is high prevalence rate in China. But many questions remain unanswered. From Feb-April 1994, 91 individuals examined by gastric endoscopy were investigated. During examination, individuals answered questions relating to life style, social conditions, education level, and economical statue in recent years. A stepwise logistic regression analysis of the data showed significant independent relationships between tissue-smear positivity and following factors: education level and raising animals. But there are no relationship of smoking, drinking with tissuesmear positivity.

关 键 词：幽门螺旋菌 危险因素 LOGISTIC回归 

分 类 号：R515[医药卫生—内科学]