甘糖酯对小鼠免疫功能的影响  

THE EFFECTS OF PGMS ON IMMUNOLOGICAL FUNCTION IN MICE

作　　者：李应全[1] 盛少虎[1] 侯琦[1] 马剑峰[1] 袁玮[1] 

机构地区：[1]山东医科大学药理学教研室,济南250012

出　　处：《中国海洋药物》1995年第3期14-16,共3页Chinese Journal of Marine Drugs

摘　　要：应用免疫学技术研究了甘糖酯对小鼠免疫功能的影响。研究发现甘糖酯口服给药可增加小鼠免疫器官重量,提高小鼠碳粒廓清速率,提高小鼠腹腔巨噬细胞的吞噬率和吞噬指数,增加小鼠ANAE^+淋巴细胞百分率,促进小鼠外周血清溶血素的生成。提示甘糖酯可增强小鼠特异性和非特异性免疫功能。The effects of Proplylene glucol mannurate sulfate (PGMS) on mice's immunological function have been studied with immunological techniques. When given orally,PGMS could enhance the weight of the mice's immunological organs and the speed of carbonparticle elimination in mice,the phagocytic rate and index of the macrophagocytes in the mice's abdominal cavity were enhanced, the percentage of ANAE' lymphocytes were increased, the production of hemolysin in mice peripheral blood were promoted. The study suggests that PGMS improves both the specific and nonspecific immunological function in mice.

关 键 词：甘糖酯 免疫功能 巨噬细胞 溶血素 

分 类 号：R977.6[医药卫生—药品]