C型肉毒梭菌毒素灭家鼠效果观察  

Observation on the Effectiveness of Botulin c in Rodent Control

作　　者：吴道余 钱立长 徐立[1] 徐伟华[1] 张家林[1] 吴万能[1] 刘春生[1] 

机构地区：[1]安徽省枞阳县卫生防疫站,安庆市卫生防疫站,安徽省卫生防疫站

出　　处：《中国媒介生物学及控制杂志》1995年第5期364-367,共4页Chinese Journal of Vector Biology and Control

摘　　要：作者于１９９４年１１～１２月在安徽省枞阳县长沙乡，用Ｃ型肉毒梭菌毒素对黄胸鼠和褐家鼠进行实验室和现场灭鼠效果观察。用灌胃法测定对黄胸鼠最小致死剂量为６４０００ＭＵ／ｋｇ体重，对褐家鼠为３２０００ＭＵ／ｋｇ体重。０．５％Ｃ型肉毒梭菌毒素大米毒饵，初遇和再遇适口性摄食系数褐家鼠为０．８６和０．６２；黄胸鼠为０．７５和０．５４．０．５％Ｃ型肉毒梭菌毒素现场灭效，鼠笼法灭鼠率为１８．０５％，粉迹法为２５．９６％；０．００５％溴敌隆毒饵灭鼠率鼠笼法为７５．６６％，粉迹法调查为７７．９５％：两者差别非常显著（Ｐ＜０．０１）．表明Ｃ型肉毒梭菌毒素对黄胸鼠和褐家鼠毒力较小。In Nov.and Dec.1994,the authors made an observation on the effectiveness of Botulin Type C in rodent control for Rattus flavepectus and Rattus norvegicus in Changsha,Zongyang County.Both laboratory and field tests were done.A minium lethal dose per kg weight of rat was obtained by enema.For Rattus flavipectus the min.lethal dose was 64000 MU and for Rattus norvegicus the dose was 32 000 MU.0.5% Botulin Type C rice bait was tested respectively.The initial and second feeding indexes of 0.75 and 0.54 for R.f.and the indexes of 0.86 and 0.62 for R.n.Then we made a comparision of the effectiveness between Botulin Type C and Bromadiolone,both in rice baits.The test showed that in cage method the killing rate for Botulin Type C was 18.08% and in powdered spots method the rate was 25.96%.For Bromadiolone the killing rate in cage method reached 75.66% while with powderd spots method it arrived at 73.95%.A significant difference was found(P<0.01).With the above we came to the conclusion that Botulin Type C was not suitable for rodents control espcirally.for the two Rattus species in some way.

关 键 词：灭鼠剂 C型 肉毒梭菌毒素 灭鼠 药效 

分 类 号：R979.8[医药卫生—药品] R184.35[医药卫生—药学]