应用氢化物发生-原子吸收法检测浓缩狂犬病疫苗中硫柳汞的含量  

Detection of Thiomersalate Content in Concentrated Rabies Vaccine by Mercury/Hydride System-Atomic Absorption Method

作　　者：孙玉杰[1] 唐巧英[1] 李岩[1] 王威 

机构地区：[1]卫生部北京生物制品研究所,北京100024

出　　处：《中国生物制品学杂志》1995年第2期77-79,共3页Chinese Journal of Biologicals

摘　　要：测定原制狂犬病疫苗中硫柳汞含量的化学比色法已不适于浓缩狂犬病疫苗。为此建立了氢化物发生－原子吸收法（MHS－AA法）。此法快速、灵敏、准确、简便，可大批量检测浓缩狂犬病疫苗和乙肝疫苗等制品中硫柳汞的含量。The chemical colormetric analysis method used for the detection of thiomersalate content in crude rabies vaccine was not suitable for concentrated rabies vaccine, so Mercury/Hydride System-Atomic Absorption (MHS-AA) method was established. The method was rapid,sensitive, accurate and simple, and it could also be used for the detection of thiomersalate content in other biological products, e. g. contentrated rabies vaccine and hepatitis B vaccine.

关 键 词：狂犬病 疫苗 硫柳汞含量 氢化物发生 原子吸收法 

分 类 号：R512.990.3[医药卫生—内科学] R392-33[医药卫生—临床医学]