高效价巨细胞病毒免疫球蛋白的制备及初步应用  

Preparation and Preliminarily Application of High Titer Cytomegalovirus IgG

作　　者：郭凤云 刘淑英[1] 张梅[1] 陈维金[1] 王玉梅[1] 刘汝丹 

机构地区：[1]卫生部长春生物制品研究所,长春130062

出　　处：《中国生物制品学杂志》1995年第3期132-134,共3页Chinese Journal of Biologicals

摘　　要：应用ELISA法筛选巨细胞病毒（CMV）IgG效价≥1：30000的人血浆，合并后，按低温乙醇法精制出高效价CMV－IgG。经小规模人体应用观察无不良反应，且有71．4％（50／70）的CMV－IgM或CMV-IgA阳性人的血清转阴。The human plasma containing high titer (≥1: 30000) cytomegalovirus(CMV)IgG was screened by ELISA and used for preparing high titer CMV-IgG by coldethanol fractionation method. Small-scale clinical trial revealed that average the patientstreated with CMV-IgG whose CMV-IgM or CMV-IgA were pos1tive with a serum averageconversion rate of 71．4％(50/70),and no adverse reaction was found.

关 键 词：巨细胞病毒 免疫球蛋白 制备 应用 

分 类 号：R373.9[医药卫生—病原生物学] R392－33[医药卫生—基础医学]