慢性肾功能不全患者骨矿含量测定的临床意义  

Clinical significance of determination of bone mineral content in chronic renal failure

作　　者：王淑芬[1] 李冀军[1] 周治中[1] 文志道[1] 

机构地区：[1]解放军第304医院肾内科

出　　处：《中国危重病急救医学》1995年第1期18-19,共2页Chinese Critical Care Medicine

摘　　要：为了探讨不同类型肾脏疾病与肾性骨病发生发展的关系，对１９９１年１～１１月诊治的６３例肾脏病患者用单光子吸收法（ｓｐＡ）测定尺、桡骨远端１／３处骨矿含量（ＢＭＣ）。６３例肾脏病患者按其肌酐清除率分Ａ、Ｂ、Ｃ３组。对比分析发现：ＢＭＣ测定值，Ａ组２７例中有２４例降低，Ｂ组２１例中有８例降低，Ｃ组全部在正常范围；ＢＭＣ测定值Ａ、Ｃ组间差异显著（Ｐ＜０．０５），Ｂ、Ｃ组间无显著差异（Ｐ＞０．０５）．说明ＢＭＣ测定值降低幅度与肌酐清除率的下降有显著的正相关系，血液透析时间与ＢＭＣ的降低幅度呈显著正相关。作者建议，可将ＢＭＣ测定用于临床监测慢性肾功能不全患者的骨代谢紊乱。The purpo se of this article was to stud y the rela-tionship between the development of renal osteo-pathy and d ifferent types o f renal d iseases.Sixty threepatients were admitted from Jan.to Nov.,1991.Thepatients were divided into A(terminal uremia),B(chronic renal fallure, CRF)and C(general renaldiseease)groups. Single photenabsorptiometry wasused to determine bone mineral content(BmC)onone th ird distalis of rad ius and ulna.The value oBM C was decreased both in group A(24/27)andgroup B(8/21); and the value was normal in all pa-tients of group C. There was a significant differencebetween group a and C(P<0.05),and no significantdifference bwtween B and C. This result showed there was a significant positive correlation betweee the de-crease of creatinine clearance rate and decrease of BMC,and!there was a significant negative correlao-tion between the time of hemodialysis and the de-crease of BM C,The authors suggest thatmeasurements of BM C be used in monitoring thedisorder of bone metabolism in patients with chronicrenal dysfunction.

关 键 词：肾功能不全 慢性 骨矿物质 

分 类 号：R692.502[医药卫生—泌尿科学] [医药卫生—外科学] [医药卫生—临床医学] ？