阿片受体与阿片类依赖的防治  

OPIOID RECEPTORS AND TREATMENT OF OPIOID DEPENDENCE

作　　者：秦伯益[1] 

机构地区：[1]军事医学科学院毒物药物研究所

出　　处：《中国新药杂志》1995年第6期3-7,共5页Chinese Journal of New Drugs

摘　　要：阿片类依赖是一种特殊的疾病。病原是外源性阿片类化合物，靶部位是阿片受体。靶部位在病原作用下所造成的一系列后效应涉及机体很多系统的功能紊乱。本综述以阿片受体为核心概要地讨论阿片类依赖的形成、戒断和康复机制，并根据这些机制探讨对阿片类依赖的诊断、治疗和康复的总体设计。Opioid dependence is a special disease。Its etiological agent is exoge-nous opioid compounds。The target is opioid receptors。A series of after-effects produced by the action of the etiological agent on the targets involve dysfunction of many systems of the organism.In the present paper,the mechanisms of formation of abstinence and rehabilitation from opioid dependence are briefly reviewed with opioid receptors as the central point.On the basis of these mechanisms,the overall design of diagnosis,treatment and rehabilitation of opioid dependence is discussed。

关 键 词：阿片受体 阿片类依赖 防治 药物依赖 

分 类 号：R595.301[医药卫生—内科学]