牛骨形成蛋白在骨不连中的临床应用  

ABSIRACTTHE CLINICAL APPLICATION OF THE BOVINE BONE MORPHOGENETIC PROTEIN MIXED WITH PLASTER OF PARIS

作　　者：白孟海[1] 葛宝丰[1] 杨超[1] 曾述强[1] 王勇[1] 陈东安[1] 

机构地区：[1]兰州市兰州军区总医院创伤骨科研究所

出　　处：《中国修复重建外科杂志》1995年第1期4-5,共2页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：应用牛骨形成蛋白（ｂｏｖｉｎｅＢｏｎｅＭｏｒｐｈｏｇｅｎｅｔｉｃＰｒｏｔｅｉｎ简称ｂ－ＢＭＰ）成功的治愈１３例骨不连病人。经过１３个月～２９个月随访观察，效果较好。本组病人术前平均已做过１．５次手术。１３例病人中，有１２例被１次治愈。１例病人再次行内固定加用牛骨形成蛋白的植入也被治愈。骨形成蛋白的应用方式，采用同锻石膏复合后植入骨不连处。平均每个病人植入１００ｍｇＢＭＰ，１３例病人平均治愈时间为４．７个月。术后没有任何并发症。hirteen patients with intractable nonunions of fractures of long bones were sueessfullytreated by a combination of internal fixation and implantation of b-BMP. There was an averageof 1.5 operative procedures per patient in an attempting to establish reunion prior to b-BMP im-ptantation. Union was obtained in 12 of the 13 patients exapt in one who gained success from es-tablish the second attempt.The average time requited to union was 4.7 months. No complication was seen.

关 键 词：牛骨形成蛋白 骨不连 煅石膏 临床应用 

分 类 号：R683.05[医药卫生—骨科学] R687.3[医药卫生—外科学]