外源性谷胱甘肽对染汞动物脏器汞含量的影响  

Effect of Exogenous Glutathione on the Content of Mercury in Organs of Mercury Exposure Rat

作　　者：孙贵范[1] 李松[1] 丁桂英[1] 王玉梅 

机构地区：[1]中国医科大学预防医学系劳动卫生教研室,阜新市劳研所

出　　处：《中国医科大学学报》1995年第6期566-568,共3页Journal of China Medical University

基　　金：国家自然科学基金资助课题

摘　　要：从动物实验角度研究了外源性谷胱甘肽（ＧＳＨ）对汞分布的影响。结果表明：染汞同时投入ＧＳＨ后，甲状腺、肝汞浓度与单纯染汞组比较各剂量组均减小，且有显著差异。肾汞低、中剂量组投ＧＳＨ后肾汞含量下降，其中低剂量组下降明显。提示，外源性ＧＳＨ可降低组织中汞含量，对汞中毒防治有重要理论及实践意义。he study was focused on the effect of exogenous glutathione(GSH)on the distribution of mercuryfrom the point of view of animal experiment. The results showed that when GSH was administered atthe same time of mercury exposure, the concentration of mercury in thyroid and liver decrease in eachgroup of different dose compared with the simple mercury exposure group significantly. After GSH wasadministered, the content of mercury in kidney decrease in low and middle dose group, especially in thelow dose group. All the results indicated that exogenous glutathione could decrease the content of mer-cury in tissues. It is of great theoretical and practical significance in prevention and cure of mercury poi-son.

关 键 词：汞中毒 防治 谷胱甘肽 动物实验 脏器 

分 类 号：R595.205[医药卫生—内科学]