核酸对机体作用的研究  

Effect of nucleic acid on somatic function in mice

作　　者：董再珍 王龙[1] 章君照 

机构地区：[1]山东大学生物学系,济南生物工程研究院

出　　处：《中国药学杂志》1995年第12期725-727,共3页Chinese Pharmaceutical Journal

摘　　要：每天小鼠ｉｇ核酸０．８ｍｇ／只，连续１５ｄ，可使红细胞数增加、血红蛋白含量升高；对腹腔巨噬细胞吞噬功能、外周血Ｔ淋巴细胞数、特异性抗体生成和胸腺重量都有促进作用；对小鼠生长发育有促进作用；并有明显的抗疲劳作用。用４ｍｇ／只大剂量ｉｇ１５ｄ血清中尿酸含量无明显增加。提示，核酸可以作为保健食品应用，是新一代食品的希望。We studied nucleic acid on somatic function in young mice. When nucleic acid(0.8mg/mouse) was administered into stomach at dose of 0. 5 ml per day for 15 days. The experimentshowed that the number of red cells and Hb markedly elevated,markedly enhanced phargocytosis,increased number of T-lymphocytes in the peripheral blood, markedly elevated antibody formingcells to produce specific antibody, and increased weight of thymus. the nucleic acid significantlypromoted growth and development of mice and relieved fatique. When nucleic acid(4 mg/mouse)was adminsterd into stomach atdose of 0. 5 ml per day for 15 days,the uric acid content in serumshowed no significant change. Thus nucleic acid could be used widely clinically and in food.

关 键 词：核酸 红细胞 免疫功能 生长发育 抗衰老 

分 类 号：Q527[生物学—生物化学] R977.9[医药卫生—药品]