急性心肌梗塞患者红细胞磷脂水平测定  

The Determination of Erythrocyte Phospholipid Levels in Patients with Acute Myocardial Infarction

作　　者：霍海洋 李廷富 吴广成[1] 范力华 许克诚 宗志宏[1] 杨 薛海晖 于秉治[1] 

机构地区：[1]第一临床学院循环内科,基础医学院生物化学教研室,中国医科大学第一临床学院急诊科,沈阳气体压缩机厂职工医院

出　　处：《中国医科大学学报》1995年第2期160-162,共3页Journal of China Medical University

摘　　要：本文测定了第１～７天急性心肌梗塞患者红细胞磷脂主要组分含量。结果表明：急性心肌梗塞患者红细胞膜的神经鞘磷脂含量较正常人明显增高；磷脂酰胆硷、磷脂酰丝氨酸、磷脂酰乙醇胺含量却较正常人明显降低。这说明急性心肌梗塞患者存在红细胞磷脂代谢紊乱，这对心肌缺血的加重可能产生不良影响。he main components of erythrocyte phospholipid (PL)were evaluated in 11 patients during thelst to 7th day after acute myocardial infarction(AMI).The results showed that the contents of sphin-gomyelin (SM)in erythrocyte were higher ,and the levels of phosphatidalcholine(PC ),phos-phatidylserine(PS)and phosphatidylethanolamine(PE)in erythrocyte were lower in patients with AMI than those in the control.It demonstrated that metabolic disturbances of erythrocyte PL usually oc-curred in the patients with AMI,which might aggravate myocardial ischemia.

关 键 词：心肌梗塞 红细胞 磷脂 

分 类 号：R542.220.2[医药卫生—心血管疾病]