电项针对缺氧缺血性脑病患者脑电双频指数的影响  

The effect of nucha electric acupuncture on bispectral index in patients with hypoxic ischemic encephalopathy

作　　者：缪文丽[1] 高维滨[2] 李海玲[1] 任红贤[1] 

机构地区：[1]解放军第四○一医院ICU,山东青岛266071 [2]黑龙江中医药大学附属第二医院,黑龙江哈尔滨150001

出　　处：《中国中西医结合急救杂志》2009年第6期359-361,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

摘　　要：目的 观察缺氧缺血性脑病(HIE)患者在电项针治疗中脑电双频指数(BIS)的变化及其临床意义.方法将20例HIE患者按格拉斯哥-匹兹堡昏迷量表评分(G-P评分)分为<12分组(4例)和≥12分组(16例);对给予常规治疗后仍昏迷者同时行电项针刺激两侧风池穴和供血穴(新穴)30 min,6d为1个疗程.比较两组电项针治疗前、治疗过程中及治疗后的BIS值,以及电项针治疗前后心率、呼吸频率、平均动脉压和潮气量的变化.结果 G-P评分<12分组电项针治疗过程中BIS值的变化无统计学意义(P均>0.05);≥12分组电项针治疗过程中及治疗后BIS值(80.4±12.1和73.2±16.6)均明显高于治疗前(57.7±18.9,P<0.01和P<0.05),且≥12分组治疗前及治疗后BIS值均明显高于<12分组(分别为19.3±12.3、23.8±19.3,P<0.05和P<0.01).电项针治疗前后心率、呼吸频率、平均动脉压、潮气量比较差异无统计学意义(P均>0.05).结论电项针能使轻、中度HIE患者大脑皮质兴奋性增高,BIS值上升,说明电项针刺激具有促醒作用.Objective To observe the change and clinical significance of bispectral index (BIS) in the nucha electric acupuncture therapy in patients with hypoxic ischemic encephalopathy ( HIE ). Methods According to Glasgow-Pittsberg (G-P) coma scale, 20 patients suffered from HIE were divided into two groups: the G-P coma scaleGl2 group (4 patients) and the G-P coma scale,l2 group (16 patients). The patients who kept unconscious after routine treatment were given nucha electric acupuncture therapy, Fengchi acupoints(风池穴)and Gongxue acupointa(供血穴，new acupoint) on the bilateral sides for 30 minutes, one therapeutic course including 6 days. The BIS value before. during and after the acupuncture therapy, and the changes of heart rate (HR), respiratory rate (RR)，mean arterial pressure (MAP) and tidal volume (Vr) before and after therapy between the two groups were compared. Results The change of BIS value during the nucha electric acupuncture therapy in the G-P coma scale<12 group had no statistical significance (all P＞O. 05)； in the G-P coma scale≥12 group, the BIS value during and after nucha electric acupuncture therapy ( 80.4±12.1, 73.2±16.6, respectively) were both significantly higher than that before therapy (57.7±18. 9, P<0. O1 and P<0. 05)，the BIS value before and after therapy in the G-P coma scale,12 group were both higher than that of the G-P coma scale<12 group (19.3±12. 3, 23. 8±19. 3, P<0. 05 and P<0. 01). Besides, there were no differences in HR, RR, MAP and Vr before and after therapy (all P＞O. 05). Conclusion The nucha electric acupuncture therapy can increase cortical excitability and BIS value of HIE patients with mild-moderate brain damage, suggesting that the therapy possess the effect of promoting consciousness.

关 键 词：电项针 脑电双频指数 缺氧缺血性脑病 

分 类 号：R459.7[医药卫生—急诊医学]