非心脏手术后认知功能障碍危险因素分析  

Analysis on risk factors of postoperative cognitive dysfunction after non-cardiac surgery

作　　者：叶辉锋 刘猛[1] 王成才[1] 

机构地区：[1]解放军第二军医大学附属长征医院麻醉科,上海200003

出　　处：《临床军医杂志》2010年第4期528-530,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨非心脏手术患者术后认知功能障碍(POCD)患病率及其危险因素。方法选择45岁以上各类手术患者175例,行全身麻醉或蛛网膜下腔麻醉。所有患者术前1d用简易智能状态检查法测试,术后1d再次测试,并记录每项测试结果。如果患者术后认知功能评分较术前低2分或以上,则认为发生POCD。分析年龄、性别、手术方式、麻醉方式、术前患高血压或(和)糖尿病等基础疾病、术后拔管时间、受教育时间及苯二氮卓类药物的应用等因素与POCD之间的关系。结果 175例患者中,29例发生POCD,患病率为16.6%。Ranksum及Logistic回归分析表明,年龄及手术方式是POCD的主要相关因素。结论中老年患者胸腹部及骨科复杂手术POCD的患病率为16.6%,且与年龄及手术方式有关。Objective To observe the incidence of postoperative cognitive dysfunction (POCD) and analyze the related factors.Methods A total of 175 patients over 45 years old underwent general anesthesia or subarachnoid space block anesthesia.All the patients were administered MMSE one day before and after surgery.A decline of 2 or more than 2 points in the results was regarded as POCD.Results There were 29 patients who got POCD.The incidence of POCD was 16.6% .Age and operative method were the main related factors.Conclusion The incidence of POCD in old patients is 16.6% .It is related to age and operative method.

关 键 词：非心脏手术 术后认知功能障碍 

分 类 号：R82[医药卫生—临床医学]