老年人药源性心律失常56例临床分析  

Analysis of 56 elderly patients with drug-induced arrhythmia

作　　者：朱辉[1] 张苏扬[1] 吴利群[1] 鲁进宇[1] 

机构地区：[1]解放军第85医院老年病房,上海200052

出　　处：《临床军医杂志》2010年第4期548-550,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨老年人药源性心律失常的临床特征。方法对56例住院老年患者药源性心律失常的用药情况、危险因素、临床表现进行回顾分析。结果老年人药源性心律失常易发生在80岁以上病人(占46.1%),注射用药(占64.3%)和联合用药(占80.4%)易发生,按引起心律失常的药物种类,以抗心律失常药(占39.3%)、抗感染药(占18.6%)和平喘药(占17.9%)多见。分析危险因素前3位依次为感染(占29.5%),慢性心功能不全(占22.9%)和传导系统病变(占18%)。结论 80岁以上老年人有感染时,若多种药联合应用,特别是应用抗心律失常药时易发生药源性心律失常。Objective To discuss the clinical features of drug-induced arrhythmia for elderly population.Methods Fifty-six elderly patients with drug-induced arrhythmia were analyzed on the aspects of drug administration,risk factors and clinical manifestations.Results Drug-induced arrhythmia occurred more often for the population who were older than 80 years of age (46.1% ) , and received drug injection (64.3% ) and combination of multiple drugs (80.4% ) .Three common types of drug that induced arrhythmia were anti-arrhythmics (39.3% ) ,anti-infectious agents (18.6% ) and anti-asthmatics (17.9% ) .The top three risk factors were infection (29.5% ) ,chronic heart failure (22.9% ) and pathological changes in conduction system (18.0% ) .Conclusion For those over 80 years old or older,the combination of multiple drugs,especially including anti-arrhythmics,will be inclined to lead to drug-induced arrhythmia.

关 键 词：心律失常 药源性 老年人 

分 类 号：R82[医药卫生—临床医学]