2型糖尿病患者合并脑梗死的相关危险因素分析  

Analysis of risk factors for diabetes mellitus with cerebral infarction

作　　者：王熙然[1] 裴育[2] 李全民[1] 王磊[1] 李颖华[1] 赵红[1] 詹志伟[1] 

机构地区：[1]解放军第二炮兵总医院,北京100088 [2]解放军总医院老年内分泌科,北京100853

出　　处：《临床军医杂志》2010年第4期570-572,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨2型糖尿病患者合并脑梗死的危险因素。方法收集448例2型糖尿病患者的临床资料,根据是否合并脑梗死将患者分为糖尿病脑梗死组和糖尿病非脑梗死组,比较可能诱发脑梗死的危险因素。结果 81例患者合并脑梗死占总数的18.1%。脑梗死组与非脑梗死组比较,年龄[(70.53±7.79)岁与(60.72±13.03)岁]、糖尿病病程[(130.25±85.77)月与(94.54±92.41)月]、踝肱指数[(0.90±0.23)与(0.98±0.19)]、尿素氮[(6.84±2.49)mmol/L与(6.17±2.21)mmol/L]、糖化血红蛋白[(9.09%±2.41)%与(8.24±1.77)%]及高血压(84.0%与59.1%)、冠心病(63.0%与43.1%)、糖尿病视网膜病变(35.8%与22.6%)、糖尿病肾病(50.6%与31.9%)、下肢动脉斑块(87.7%与70.3%)的合并率两组之间的差异均有统计学意义(P<0.05)。Logistic回归显示年龄(P=0.000)、糖化血红蛋白(P=0.027)与脑梗死的发生密切相关。结论年龄、糖化血红蛋白升高为影响2型糖尿病脑梗死的主要危险因素,积极控制血糖可减少脑梗死的发生。Objective To investigate the risk factors of cerebral infarction among diagnosed type 2 diabetic patients.Methods Clinical data were collected in 448 patients with type 2 diabetes.All the patients were divided into two groups according to the complication of cerebral infarction.There were 81 patients (18.1% ) complicated with cerebral infarction.Results Between complication group and non-complication,there were statistically significant differences in age (70.53±7.79 vs 60.72±13.0 years) , diabetic duration (130.25±85.77 vs 94.54±92.41 months) ,ankle brachial index (0.90±0.23 vs 0.98±0.19) ,urea nitro-gen(6.84 ±2.49 vs 6.17 ±2.21 mmol/L) ,HbA1c (9.09%±2.41% vs 8.24%±1.77% ) ,and rates of hypertension (84.0% vs 59.1% ) ,coronary heart disease (63.0% vs 43.1% ) ,diabetic retinopathy (35.8 vs 22.6% ) ,diabetic kidney disease (50.6% vs 31.9% ) and lower limb arterial plaque of merger (87.7% vs 70.3% ) (P<0.05) .The result of logistic regression showed that age (P=0.000) and HbA1c (P=0.027) were related strongly to diabetes complicated with cerebral infarction.Conclusion Age and HbA1c are the risk factors in type 2 diabetic patients with cerebral infarction.Proper blood glucose control is an effective way to prevent cerebral infarction.

关 键 词：糖尿病 脑梗死 危险因素 

分 类 号：R82[医药卫生—临床医学]