纳米羟基磷灰石对血管内支架用可降解Mg-Zn-Zr合金性能的影响  

Effects of Nanohydroxyapatite Addition on Properties of Mg-Zn-Zr Alloy for Biodegradable Intravascular Stents

作　　者：王晓伟[1] 陈民芳[1,3] 由臣[1,4] 刘德宝 魏军[2] 

机构地区：[1]天津理工大学,天津300384 [2]新加坡制造技术研究所,新加坡638075 [3]天津市光电显示材料与器件重点实验室,天津300384 [4]显示材料与光电器件省部共建教育部重点实验室,天津300384

出　　处：《稀有金属材料与工程》2010年第12期2211-2216,共6页Rare Metal Materials and Engineering

基　　金：国家自然科学基金项目(51071108);天津市自然科学基金重点项目(09JCZDJC18500)

摘　　要：作为可降解血管内支架材料的探索,制备了Mg-3Zn-0.8Zr合金(质量分数,%,下同)及Mg-3Zn-0.8Zr-1HA复合材料,研究了纳米羟基磷灰石(n-HA)对合金力学性能和生物腐蚀降解性能的影响。n-HA均匀分布于镁合金基体中,使晶粒细化,抗拉强度和延伸率均高于未添加n-HA合金。模拟体液(SBF)浸泡实验表明:随着浸泡时间延长,两种材料表面形貌差异明显。浸泡20d后,含n-HA的复合材料表面完整,有Ca、P沉积层形成,电化学测试计算的电流密度为0.701×10-5A.cm-2;而不含HA的合金表面严重脱落形成凹坑,对应腐蚀电流密度为1.034×10-5A.cm-2,显示n-HA显著增加了镁合金的耐腐蚀能力。To explore biodegradable intravascular stents, Mg-3Zn-0.8Zr-1HA composite (mass fraction, similarly hereinafter) and Mg-3Zn-0.8Zr alloy were prepared to investigate the effects of nanohydroxyapatite (n-HA) on the mechanical and biodegradable properties of Mg-3Zn-0.8Zr alloy. Results indicate that the n-HA particles are distributed uniformly in the matrix, so the grains of the matrix are refined, and the ultimate tensile strength and elongation are increased. The immersion tests in the simulated body fluid (SBF) show that the surface morphologies of the two kinds of materials are quite different as the immersion time is prolonged. After immersion for 20 d, the surface of the composite with n-HA is still perfect and covered with Ca and P, while a lot of pitting occurs on the surface of Mg-3Zn-0.8Zr alloy. The electrical current densities of the composite and the alloy are 0.701x10(-5) A.cm(-2) and 1.034x10(-5) A.cm(-2) respectively, which demonstrates that the corrosion resistance of the Mg alloy is significantly improved by the addition of nanohydroxyapatite powders.

关 键 词：纳米羟基磷灰石 血管内支架 可降解 合金性能 n-HA 复合材料 腐蚀电流密度 材料表面 镁合金基体 浸泡实验 合金力学性能 耐腐蚀能力 质量分数 支架材料 生物腐蚀 模拟体液 抗拉强度 均匀分布 晶粒细化 浸泡时间 

分 类 号：TG146.22[一般工业技术—材料科学与工程]