脑梗死复发危险因素分析  

The Analysis of Risk Factors of Recurrence of Cerebral Infarction

作　　者：苏微微[1] 易兴阳[1] 李强[1] 

机构地区：[1]温州医学院附属第三医院,浙江瑞安325200

出　　处：《浙江预防医学》2010年第11期7-9,共3页Zhejiang Journal of Preventive Medicine

摘　　要：目的探讨脑梗死复发危险因素,为脑梗死防治提供理论依据。方法分析48例复发脑梗死患者和124例初发脑梗死患者的年龄、性别、吸烟、酗酒及高血压、糖尿病、冠心病、TIA病史等危险因素;测定血小板聚集率,筛选阿司匹林抵抗者,并统计分析两组危险因素差异性。结果单因素卡方检验显示阿司匹林抵抗、高血压、糖尿病、高脂血症和男性是脑梗死复发的重要危险因素。Logistic回归分析显示高血压、糖尿病、高脂血症和男性与脑梗死复发关系密切。OR值分别为6.981、4.952、2.945和2.525。结论高血压、糖尿病、高脂血症和男性是脑梗死复发的重要独立危险因素,此外阿司匹林抵抗可能也是脑梗死复发的独立危险因素。Objective To investigate the risk factors of recurrent cerebral infarction,providing a new theoretical basis for the prevention and treatment of cerebral infarction.Methods Aspirins were taken by 48 patients with recurrent cerebral infarction(recurrent group) and 124 patients without recurrent cerebral infarction(no recurrent group),200mg per day.After 7～10 days,platelet aggregation rate was tested and the patients of aspirin resistance were detected.Results Single-factor analysis showed that aspirin resistance,hypertension,diabetes,hyperlipidemia and male were important risk factors for recurrence of cerebral infarction.Multiple logistic regression analysis showed that the recurrent cerebral infarction was correlated closely with hypertension,diabetes,hyperlipidemia and male,and the OR values were 6.981,4.952,2.945 and 2.525,respectively.Conclusion Hypertension,diabetes,hyperlipidemia and male are important independent risk factors for recurrence of cerebral infarction.Besides,aspirin resistance maybe an independent risk factor for recurrent cerebral infarction.Controlling these risk factors would be very important for avoiding recurrence of cerebral infarction.

关 键 词：脑梗死 复发 危险因素 阿司匹林抵抗 

分 类 号：R1[医药卫生—公共卫生与预防医学]