密蒙花方对单纯型糖尿病视网膜病变患者视网膜功能的影响  

Effect of Buddleia prescription on the visual function in non-proliferative diabetic retinopathy

作　　者：接传红[1] 高健生[1] 严京[1] 郭欣璐[1] 宋剑涛[1] 陈子燕[1] 袁敏立[1] 赵丹丹[1] 

机构地区：[1]中国中医科学院眼科医院,北京100040

出　　处：《中国中医眼科杂志》2010年第6期323-325,共3页China Journal of Chinese Ophthalmology

摘　　要：目的观察密蒙花方对单纯型糖尿病视网膜病变眼底荧光血管造影(FFA)、视野平均敏感度(MS)、视网膜电图震荡电位(ERG-OPs)的影响。方法将确诊为气阴两虚的单纯型糖尿病视网膜病变患者63例(112只眼)随机分为治疗组及对照组,分别给予密蒙花方及羟苯磺酸钙治疗,连续用药3个月。观察治疗前后FFA和视野MS、ERG-OPs的变化。结果治疗组FFA表现改善优于对照组(P<0.01);治疗组和对照组MS均提高(P<0.05),但治疗组优于对照组;治疗组OPsO1峰潜伏期缩短(P<0.05)。结论中药密蒙花方可改善单纯型糖尿病视网膜病变的眼底情况,提高视野MS值,对ERG-OPs也有一定的作用,使视网膜血流情况稳定,是防治早期糖尿病视网膜病变的有效药物。OBJECTIVE To observe the changes of fundus fluorescein angiography(FFA),vision field mean sensitivity(VFMS)and ERG-OPs of non-proliferative diabetic retinopathy patients by Buddleia prescription.METHODS Sixty-three cases(112 eyes) of non-proliferative diabetic retinopathy patients who were diagnosed with Qi and Yin deficiency were randomly divided into therapeutic and control groups,and Buddleia prescription and Calcium Dobesilate were given respectively.After three months of treatment,the FFA,VFMS and ERG-OPs were checked.RESULTS The improvement of FFA in the treatment group was superior to the control group(P<0.01).VFMS was improved in both groups(P<0.05),but the treatment group was better than the control group.The latent period of OPs O1 was shorter(P<0.05).CONCLUSIONS Buddleia prescription could improve the fundus condition,increase VFMS,affect ERG-OPs and stabilize the retinal blood flow of non-proliferative diabetic retinopathy patients.It was an effective drug for preventing and treating non-proliferative diabetic retinopathy.

关 键 词：密蒙花 单纯型糖尿病视网膜病变 患者 视网膜功能 diabetic RETINOPATHY 治疗组 对照组 视网膜电图震荡电位 眼底荧光血管造影 视野 视网膜血流 羟苯磺酸钙 OPs FFA 有效药物 气阴两虚 连续用药 峰潜伏期 敏感度 ERG 

分 类 号：R276.7[医药卫生—中医五官科学]