2型糖尿病自主神经损害检测方法及意义  

The Test Methods and Significance of Autonomic Nerve Damage in Type 2 Diabetes

作　　者：李晶玉[1] 李海平[1] 丁希艳[1] 李威[1] 许振波[2] 

机构地区：[1]北华大学附属医院神经内科,吉林吉林132011 [2]北华大学附属医院内分泌科,吉林吉林132011

出　　处：《慢性病学杂志》2010年第12期1585-1587,共3页Chronic Pathematology Journal

摘　　要：目的探讨2型糖尿病自主神经损害的检测方法及意义。方法对46例2型糖尿病患者进行心率变异(HRV)及皮肤交感反射(SSR)检测。结果 SSR:病程≤5a与病程>5a组之间阳性率差异有统计学意义。HRV:病程≤5a与病程>5a组阳性率有统计学差异。在病程≤5a组中SSR与HRV检测结果有统计学差异。病程>5a组中HRV与SSR无统计学差异。结论 2型糖尿病病程≤5a的患者自主神经检测SSR的异常率要高于HRV。病程>5a组SSR异常率高于≤5a组。病程>5a组HRV异常率高于≤5a组。2型糖尿病患者不论病程≤5a或>5a,HRV检测各项指标(SDNN、SDANN、RMSSD)之间,同一指标内的各组群间均无统计学差异。Objective To discuss the test methods and significance of autonomic nerve damage in type 2 diabetes. Method 46 cases of type 2 diabetes patients perform heart rate variability (HRV) and sympathetic skin reflex (SSR) test.Results Test results of SSR and HRV:The positive rate have significant difference between groups with course of diseases ≤5 years and course of diseases ≥5 years. The test results of SSR and HRV show significant differences in the group with course of diseases ≤5 years. The differences of SSR and HRV are not significant in the group with course of diseases >5 years.Conclusion The positive rate of SSR is higher than that of HRV on autonomic nerve damage,when patients with type 2 diabetes and with course of diseases≤5 years. The positive rate of SSR of the patients with course of diseases> 5 years is higher than that of the patients with course of diseases≤5 years. The positive rate of HRV of the patients with course of diseases> 5 years is higher than that of the patients with course of diseases≤5 years. When perform SSR test in the type 2 diabetes patients,no matter if the course of diseases≤5 years or the course of diseases> 5 years,there are no significant differences among the index of SDNN,SDANN and RMSSD.

关 键 词：糖尿病 2型/并发症 自主神经系统疾病/病因学/诊断 

分 类 号：R58[医药卫生—内分泌]