呼吸道感染铜绿假单胞菌耐药特点分析  

Analysis of the bacterial resistance of respiratory tract infection with Pseudomons aeruginosa

作　　者：张芳[1] 尹德明[1] 

机构地区：[1]北京市通州区潞河医院检验科

出　　处：《医学检验与临床》2006年第3期12-13,共2页Medical Laboratory Science and Clinics

摘　　要：目的分析呼吸道感染铜绿假单胞菌的耐药性,为临床用药提供参考.方法收集北京潞河医院2002年10月～2004年10月住院病人呼吸道标本分离的铜绿假单胞菌136株,药敏使用Micnoscan微量稀释法并对结果进行分析.结果136株铜绿假单胞菌敏感性最高的抗菌药物是哌拉西林/他唑巴坦(94,1%),其次分别为哌拉西林(89.7%)、亚胺硫霉素(85.3%)、头孢他啶(79.4%)、环丙沙星(77.9%).结论铜绿假单胞菌是临床常见致病菌,耐药性严重.治疗中应根据分离株耐药特点选择合理用药方案,避免多重耐药铜绿假单胞(MD RP)的出现.Objective To analysis the bacterial resistance of respiratory, tract infection with Pseudomonas aemginosa(PA),and to providereference for clinical therapy.Methods A total of 136 isolates of PA were collectedfrom respiratory samples of patients from Octorber,2002 to Octorber,2004.The broth microdilution test if Microscan were used.The laboratory data were analysised.Results The susceptible rates of PA,strains topiperacillin/tazobactam,piperacillin,imipenem,cefiazidime and ciprofloxacin were94.1%,89.7%,85.3%,79.4% and 77.9% respectively.Conclusions Theinfection caused by PA is common in clinics.The problem of drug resistance is very serious Antimicrobial agents should chosen according to the results of antimicro bialsusceptibility.It is important to avoid multi-drug resistant Pseudomonasaeruginosa(MDRP).

关 键 词：呼吸道感染 铜绿假单胞菌 耐药特点 哌拉西林 临床常见致病菌 耐药性 亚胺硫霉素 微量稀释法 住院病人 用药方案 头孢他啶 他唑巴坦 目的分析 临床用药 抗菌药物 环丙沙星 多重耐药 敏感性 分离株 治疗 

分 类 号：R446.5[医药卫生—诊断学]