17335例乙肝PreS_1抗原检测结果分析  

The result analysis of HBV PreS_1 antigen for 17335 specimens

作　　者：张岩[1] 杨琴[1] 陈燕[1] 曲少莲[1] 袁美莲[1] 连丽峰[1] 

机构地区：[1]胜利油田中心医院检验科,东营257034

出　　处：《医学检验与临床》2006年第6期41-42,共2页Medical Laboratory Science and Clinics

摘　　要：目的探讨PreS1抗原检测在乙肝早期诊断和预后以及病毒复制方面的意义。方法采用酶免法,用瑞士产酶免工作站MRp150进行检测,并对检测结果进行统计分析。结果PreS1Ag阳性率高于HBeAg阳性率,PreS1Ag与病毒复制指标HBeAg密切相关,但两者用来判断乙肝病毒的活动性和复制的应用价值并不相完全等同,Pres1Ag比HBeAg更敏感,代表的范围更广。结论Pres1的测定有助于临床对急慢性肝炎治疗效果和预后的评估。Objective PreS_1 antigen in the early diagnosis and prognosisof hepatitis B viral replication and the significance.Methods ELiSA,enzyme immunoassay using Swiss production workstations MRP150 weremeasured,the results were statistically analyzed,results PreS_1Ag HBeAg positive rate was higher than the results,PreS_1Ag closely associated withviral replication in HBeAg indicators,But both used to judge thereplication of hepatitis B virus activity and do not match exactly thesame value.PreS_1Ag more sensitive than HBeAg,the representative of a widerrange.Conclusion PreS_1 contribute to the determination of clinicalprognosis and treatment of acute and chronic hepatitis assessment.

关 键 词：乙肝病毒 抗原检测 检测结果分析 病毒复制 阳性率 诊断和预后 治疗效果 应用价值 统计分析 慢性肝炎 复制指标 完全等 酶免法 活动性 工作站 瑞士 评估 临床 方法 测定 

分 类 号：R446.6[医药卫生—诊断学]