肺结核合并淋巴瘤的临床病理分析  

Clinical analysis of pulmonary tuberculosis combined malignant lymphoma

作　　者：张炎林 袁保东 肖勇 胡明 王娅 

机构地区：[1]湖北武汉市肺科医院武汉市结核病防治所,430030

出　　处：《中华检验医学杂志》2005年第8期799-801,共3页Chinese Journal of Laboratory Medicine

摘　　要：目的探讨肺结核合并淋巴瘤的临床病理特征和发病机理。方法回顾分析18例已确诊的肺结核并发淋巴瘤的临床病理特征、影像学特点和治疗情况。结果18例中均为浸润性肺结核,其中13例为陈旧性肺结核,5例为涂阳肺结核;18例中霍奇金淋巴瘤5例,非霍奇金淋巴瘤13例;肺结核在淋巴瘤之前有16例,淋巴瘤在肺结核之前有2例;无结核病和淋巴瘤同时发现的病例。淋巴瘤病人可以患肺结核,可能与淋巴瘤放化疗后导致机体免疫紊乱,从而引起结核的发生。结论在结核病的高发地区,结核病和淋巴瘤可同时存在同一病人,及时行必要的有创检查获得组织病理标本有利于早期诊断。Objective To discuss the Clinical character of pulmonary tuberculosis combined malignant lymphoma and its Pathogenesis, and to review the literature. Methods Eighteen cases of pulmonary tuberculosis combined malignant lymphoma from 1996 to 2003 were retrospectively analyzed by its clinical manifestations, X-ray features, diagnosis and treatments. Results 18 cases were all infiltrative pulmonary tuberculosis, 13 them were calcification locals,5 were active pulmonary tuberculosis;5 of all were Hodgkin＇ s lymphomas, 13 of all were non-Hodgkin＇ s lymphomas. 16 cases were lymphomas after tuberculosis, 2 cases tuberculosis after lymphomas, none were co-existent malignant lymphoma and tuberculosis. Tuberculosis may precede or complicate a lymphomatous process during the development of beth diseases,This might is linked to immune deficiency and chronic inflammation; Lymphomas might cause pulmonary tuberculosis, it might cause the immune turbulence of an individual, Pulmonary tuberculosis infection occurring during or after the radiotherapy and chemotherapy of lymphoma. Conclusions It may pulmonary tuberculosis combined malignant lymphoma in the patients in the endemic areas of tuberculosis,Appropriate invasive biopsy procedures are necessary for early diagnosis.

关 键 词：结核 肺 淋巴瘤 病理学 临床 诊断 非霍奇金淋巴瘤 浸润性肺结核 临床病理分析 临床病理特征 陈旧性肺结核 同一病人 

分 类 号：R521[医药卫生—内科学] R733.1[医药卫生—临床医学]