3,4-二甲氧基苯乙腈及其杂质的气相色谱分析  

Determination of 3,4-Dimethoxy Phenyl Acetonitrile and the Impurities by Gas Chromatography

作　　者：王树娟[1] 李娇[1] 李伟[1] 范志先[1] 

机构地区：[1]青岛科技大学化工学院,山东青岛266042

出　　处：《精细化工中间体》2010年第6期67-69,共3页Fine Chemical Intermediates

摘　　要：采用GC-FID,采用内标法测定了3,4-二甲氧基苯乙腈含量,外标法测定了杂质邻苯二酚、藜芦醇含量,对3,4-二甲氧基苯乙腈、邻苯二酚和藜芦醇的色谱分离条件进行了优化。3,4-二甲氧基苯乙腈的添加平均回收率为99.8%～100.1%,RSD 0.96%,准确度和精密度均能满足常量分析的要求;邻苯二酚和藜芦醇的检出限分别为100 mg/kg和50 mg/kg。An internal standard method were studied for quantitative analysis of 3,4-dimethoxy phenyl acetonitrile by GC-FID,and an external standard method for quantitatively determinate the impurities pyrocatechol and veratryl alcohol.The average recovery of 3,4-dimethoxy phenyl acetonitrile was 99.8～100.1%,and RSD was 0.96%.The accuracy and precision could meet the requirements of constant analysis.The chromatographic conditions of 3,4-dimethoxy phenyl acetonitrile,pyrocatechol and veratryl alcohol were defined.The...

关 键 词：3 4-二甲氧基苯乙腈 GC-FID 邻苯二酚 藜芦醇 内标法 外标法 

分 类 号：TQ246.7[化学工程—有机化工]