贝那普利与缬沙坦联合应用对原发性高血压的心脏保护作用  

PROTECTIVE EFFECTS OF COMBINATION OF BENAZEPRIL AND VALSARTAN TO PRIMARY HYPERTENSION'S HEART

作　　者：郭华林[1] 

机构地区：[1]南阳理工学院张仲景国医学院,河南南阳473004

出　　处：《南阳理工学院学报》2010年第6期65-67,共3页Journal of Nanyang Institute of Technology

摘　　要：目的:观察抗高血压药贝那普利与缬沙坦联合应用对原发性高血压的心脏保护作用。方法:对原发性高血压左心室肥厚患者109例,采用缬沙坦联合贝那普利治疗,疗程6个月。用药前后测定高敏C反应蛋白与左心室厚度。结果:与治疗前比较,高敏C反应蛋白(hsCRP)下降,收缩压与舒张压明显下降,舒张末期左室后壁厚度(LVPWD)、舒张末期室间隔厚度(IVST);较治疗前显著下降,差异有统计学意义。结论:对原发性高血压病人,有协同作用的降压药联合应用,能降低高血压的血管炎症作用,同时逆转左心室肥厚,对心脏有保护作用。Objective: To observe the heart protective effect of anti-hypertensive drugs Benazepril and Valsartan which are applied to cure primary hypertension together. Method: The 109 primary hypertension patients with left ventricular hypertrophy are cured by Benazepril and Valsartan together for six months. The high sensitivity C-reactive protein (hsCRP) and left ventricular thickness were detected before and after the treatment. Results: Compared with before treatment, the high sensitivity C-reactive protein (hsC...

关 键 词：贝那普利 缬沙坦 高敏C反应蛋白 原发性高血压 左心室肥厚 

分 类 号：R544.1[医药卫生—心血管疾病]