脑泰通颗粒对血管性痴呆大鼠机体状态及海马SS含量的影响  

Effects of Naotaitong Granul on Corporeal State and Somatostain Level of Rats with Vascular Dementia

作　　者：周海哲[1] 袁普卫[2] 李军[1] 

机构地区：[1]陕西中医学院,陕西咸阳712083 [2]西安交通大学第二医院,陕西西安710042

出　　处：《中国中医基础医学杂志》2005年第8期583-584,共2页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：陕西省科技厅自然科学基金资助项目(97SM62)

摘　　要：目的:研究脑泰通颗粒治疗痰瘀交结型血管性痴呆的机制。方法:通过建立血管性痴呆(痰瘀交结型)动物模型,以脑复康为阳性对照药物,从大鼠机体状态、大脑海马中SS含量进行比较。结果:脑泰通颗粒可以改善模型大鼠机体状态,提高脑组织中SS水平,与模型组比较差异有显著性。结论:脑泰通颗粒具有改善模型大鼠机体状态的功能,提高脑组织中SS含量,对控制和延缓血管性痴呆的发生具有重要作用。Objective： To investigate the mechanism of Naotaitong Granul for treating Vascular Dementia （VD）of syndrome of combination of phlegm and stasis. Methods：The subject rats were divided into Naotaitong gorup and control group. Naotaitong group was given Naotaitong. The control group was given Piracetam. After treatment, the corporeal state of rats and the level of somatostain （ss）in hippocampi of two group was evaluated and examined. Results： The corporeal state of Naotaitong group is obviously better than that of control group and the level of ss in Naotaitong group is significantly higher than that in control group. Conclusion： Naotaitong granul can improve the corporeal state of rats and increase the level of ss in brain tissue. It plays a great role in controlling and delaying the incurrence and development of VD.

关 键 词：脑泰通颗粒 血管性痴呆 痰瘀交结证 生长抑素 

分 类 号：R285.5[医药卫生—中药学]