茄根酸性组分对牙周炎炎症相关细胞因子含量的影响  

The Influence of the Acidic Components of Aubergine Root to Cytokine in Periodontitis

作　　者：汪鋆植[1] 沈映君[2] 崔帮平[1] 叶红[1] 

机构地区：[1]三峡大学,湖北宜昌442002 [2]成都中医药大学,四川成都610075

出　　处：《时珍国医国药》2005年第9期860-861,共2页Lishizhen Medicine and Materia Medica Research

摘　　要：目的:探明茄根酸性组分的抗炎机理。方法:制备大鼠牙周炎模型,治疗一周后用放免法测定牙龈组织中细胞因子白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、肿瘤坏死因子α(TNF-α)的含量。结果:茄根酸性组分能显著对抗牙周炎大鼠牙龈组织中TNF-αI、L-6I、L-8的升高。结论:茄根酸性组分具有拮抗炎性细胞因子效应。能有效地抑制IL-6和TNF-α的分泌,对牙周炎的治疗发挥积极作用。Objective： Research on the anti-inflammatory mechanism of the acidic components of Aubergine root. Methods： Made rats periodontitis model, treated with drugs. After a week, measured the contents of interferon-6, interferon-8, tumor necrosis factor-α in tissue of gum with radioimmunoassay（RIA）. Results： Compare with the model, the acidic components of aubergine root significantly reduced contents of interferon-6,interferon-8, tumor necrosis factor-α in tissue of periodontitis gum. Conclusion：The acidic components of aubergine root significantly decrease the content of inflammatory cytokines as IL-6 and TNF-α.

关 键 词：茄根 酸性组分 牙周炎 细胞因子 

分 类 号：R285.5[医药卫生—中药学]