幽门螺杆菌中国菌株插入序列IS607的分布  

Distribution of Insertion Sequence 607 of Helicobacter Pylori for China Strains

作　　者：张茂俊[1] 尤元海[1] 何利华[1] 王振宇[2] 周增芬[3] 张建中[1] 

机构地区：[1]中国疾病预防控制中心传染病预防控制所,北京昌平102206 [2]香港大学皇家玛丽医院 [3]昆明医学院第一附属医院

出　　处：《疾病监测》2005年第7期350-352,共3页Disease Surveillance

基　　金：本研究由国家自然科学基金资助NSFC30370078

摘　　要：目的分析来源于不同人群,不同临床诊断结果的幽门螺杆菌中国菌株插入因子IS607的分布。方法采用特异引物聚合酶链式反应(PCR)检测IS607特异DNA序列。并对IS607的分布进行统计分析。结果中国菌株IS607的阳性率为24%(25/105),不同人群IS607的分布没有显著差异。不同临床诊断结果分离菌株IS607的分布没有显著差异。结论幽门螺杆菌IS607的分布与菌株分离来源的人群分布及临床症状没有显著关系。Objective This study was desired to investigate the distribution of IS607 in Helicobacter pylori from different populations and different clinical outcomes in China. Methods Specific PCR amplification of IS607 from different strains was carryed out; and the distribution of IS607 was analyzed according to the isolations from different population groups and clinical background characteristics statistically. Results 25 of 105 tested Hp strains had IS607; there was no significant difference of the distribution of IS607 among different populations and different clinical outcomes. Conclusions The present of IS607 in Hp may not relate to the host people population and clinical outcome,significantly.

关 键 词：幽门螺杆菌 插入因子 IS607 

分 类 号：R378[医药卫生—病原生物学]