丹参三七组方配比优选及信息综合评价  

The optimization of different combinations and distributions between Danshen and Sanqi along with synthetical information evaluation

作　　者：商洪才[1] 高秀梅[1] 郭利平[1] 张萌[1] 潘桂湘[1] 张伯礼[1] 

机构地区：[1]天津中医学院中医药研究中心,天津300193

出　　处：《药品评价》2005年第3期209-211,共3页Drug Evaluation

基　　金：国家重点基础研究发展规划项目资助(G1999054403)

摘　　要：配伍配比是方剂的核心与灵魂所在,是中医药的特色和优势,它既不是简单的药物作用在数量上的相加,也不是机械的毒副反应的抵消,而是在辨证立法基础上,以法统方,立方遣药,有序组合而成的有制之师。本研究以复方丹参方中的丹参、三七为对象,采用整体动物模型和离体细胞模型,对二者的配伍配比进行了优选研究,并利用数学方法对实验所得生物信息进行综合评价,得到适宜配比,为中成药的二次开发建立了一种新模式。Combinations and distributions are the core of formula, It is not simple adding of different components, but is well-regulated combination, Our group had been studying the optimization of different combinations and distributions between Danshen and Sanqi in vivo or vitro for 3 years. We also evaluated synthetically experimental information by mathematics method and established a mode for the second development of some simple, characteristic and effective formulas.

关 键 词：丹参 三七 配比优选 信息综合评价 

分 类 号：R289[医药卫生—方剂学]