重型脑损伤后继发神经源性肺水肿的治疗  

Therapy of neurogenic pulmonary edema after severe head injury

作　　者：关新明[1] 

机构地区：[1]湖北省江汉油田中心医院,湖北潜江433124

出　　处：《医学信息（西安上半月）》2005年第9期1145-1146,共2页Medical Information

摘　　要：目的探讨神经源性肺水肿的病因、诊断及治疗方法。方法回顾分析7例重型脑损伤后继发神经源性肺水肿患者救治情况及综合数点经验。结果临床资料提示血中儿茶酚胺(CA)升高造成肺泡萎陷、肺泡腔及肺间隙水肿,是引起通气和换气功能障碍、出现呼吸困难及严重缺的主要原因。采用降低颅内压、及时气管切开、机控呼吸及应用血管活性物质等综合治疗措施,使4例患者获救。结论本病起病急、病情凶险、死亡率高,早期诊断及合理治疗可提高其治疗效果。Objective To investigate the etiopathogenesis, diagnosis and treatment of neurogenic pulmonary edema （NPE）. Methods The courses of treatment of six patients with secondly neurogenic pulmonary edema after severe head injuries were reviewed,and several experiences were summed up. Results The clinical data show that serum levels of catecholamine （CA）increased significantly after severe head injury.These are the main factors leading to alveoli collapse,alveolar cavity,and alveolar space edemas and causing dysfunction of gaseous exchange, dyspnea and hypoxia.There were 4 patients cured after general treatment. Conclusion NPE is a very severe and fatal disease.The mortality is very high.The effect of therapy may be improved by early diagnosis and reasonable treatment.

关 键 词：脑损伤 神经源性肺水肿 治疗 继发神经源性肺水肿 脑损伤后 治疗方法 重型 血管活性物质 综合治疗措施 患者救治 

分 类 号：R651.15[医药卫生—外科学] R269.511.5[医药卫生—临床医学]