超声组织定征对中毒兔肝脏的实验研究  

Experimental Study on Liver of Poisoning Rabbits by Ultrasonic Tissue Characterization

作　　者：曹军英[1] 李惠民[2] 刘士远[2] 肖湘生[2] 

机构地区：[1]沈阳军区总医院门诊部超声室,110016 [2]第二军医大学长征医院影像科

出　　处：《中国医学计算机成像杂志》2005年第4期279-281,共3页Chinese Computed Medical Imaging

摘　　要：目的:探讨背向散射积分技术描述急性有机磷中毒兔肝脏改变的价值。材料和方法:建立兔急性有机磷中毒动物模型,分别于染毒前(T0)、染毒后(T1至T7)8个时间点行二维超声及IBS检查。二维超声观察肝脏的回声,测量肝右叶前后径,IBS定量分析肝脏改变。结果:肝实质回声、肝右叶前后径于给药后各时间点未见明显变化。中场、远场IBS%从T4开始(T4至T7)与T0相比差异有显著性意义(P<0.05),而近场IBS%从T5开始(T5至T7)与T0相比差异有显著性意义(P<0.05)。T4至T6中、远场IBS%与近场相比,差异有显著性意义(P均<0.05),T7时近、中、远场IBS%两两相比差异均有显著性意义(P均<0.05)。结论:急性有机磷中毒兔肝脏IBS%的改变可以反映病理变化。Purpose： To explore the value of ultrasonic integrated backscatter （IBS） of liver in acute organophosphorus poisoning rabbits. Materials and Methods： Animal models of acute organophosphorus poisoning were induced. Ultrasonic examinations were performed at the times before（T0） and after （T 1 - T7） the rabbits were poisoned. The echo and the thickness of right lobe were evaluated by two- dimension ultrasound. The changes of parenchyma were quantitatively analyzed by IBS. Results： No significant changes were found in the echo and the thickness of right lobe. Significant difference of IBS% in medial and far fields was found from T4 to T7 compared with that at TO while the same change appeared from T5 to T7 in near field. From T4 to T6, IBS% of medial and far fields were significant different from that of near field respectively. Significant difference can be found between any two of the three fields at T7. Conclusion： Changes of poisoning liver IBS% can reflect pathological changes.

关 键 词：急性有机磷中毒 肝脏 背向散射积分 兔 肝脏改变 超声组织定征 实验研 背向散射积分技术 肝实质回声 二维超声 

分 类 号：R595.4[医药卫生—内科学] R512.806[医药卫生—临床医学]