高血压患者颈动脉与左心室结构和功能改变的超声研究  

Ultrasound study on carotid artery and left ventricular structures and functions in patients with hypertension

作　　者：孙健[1] 陈湘[1] 罗伟权[1] 刘海平[1] 

机构地区：[1]528400,广东省中山市,广州中医药大学中山附属医院超声诊断科

出　　处：《中华医学超声杂志（电子版）》2005年第2期107-109,共3页Chinese Journal of Medical Ultrasound(Electronic Edition)

摘　　要：目的探讨高血压患者颈动脉与左心室结构和功能改变的相关性.方法采用高频超声检测78例原发性高血压患者和30例正常对照者的颈动脉结构和功能,并与超声心动图检测的左心室结构及功能作对照研究,探讨两者的相关性.结果高血压患者的颈动脉内膜-中层厚度(IMT)、收缩末期内径(Ds)、舒张末期内径(Dd)和血流阻力指数(RI)均有增大(P＜0.05或P＜0.01),并且在左心室肥厚组更为明显;颈动脉IMT、扩张性(CD)及顺应性(CC)与左心室重量指数(LVMI)、二尖瓣环舒张早期最大血流速度E峰与舒张晚期最大血流速度A峰比值(E/A)及二尖瓣环舒张早期及晚期峰值速度e、a峰比值(e/a)密切相关(P＜0.05或P＜0.01),而与左心室射血分数(LVEF)无明显相关性.结论高血压患者颈动脉结构和功能的改变与左心室肥厚及左心室舒张功能降低密切相关.Objective To evaluate the alterations of the structures and functions of the carotid artery and left ventricle and their correlation in hypertension patients. Methods Seventy-eight patients with essential hypertension and 30 normal controls were studied, The structures and functions of the carotid artery and the left ventricle were assessed by uhrasonography and compared with the control subjects. Results The carotid intima-media thickness （IMT）, systolic diameter （Ds）, diastolic diameter （Dd） and resistance index （RI） showed an increase in the hypertension patients and were increased along with left ventricular mass index （LVMI）. The carotid distensibility （CD） and compliance （CC） showed significant decrease in the the hypertension patients. The IMT, CD, and CC had close relationship with LVMI, mitral inflow velocity E/A ratio and mitral annular velocity e/a ratio（ P 〈0.05 or P 〈0.01 ） , while had nothing with left ventricular ejection fraction （LYEF）. Conclusions The changes of the structures and functions of the carotid artery have close relationship with the left ventricular hypertrophy and the left ventricular diastolic function in hypertension patients.

关 键 词：高血压 颈动脉 左心室功能 超声心动描记术 原发性高血压患者 左心室结构 颈动脉结构 功能改变 超声研究 最大血流速度 

分 类 号：R544.1[医药卫生—心血管疾病] R459.5[医药卫生—内科学]