声学定量技术评价充血性心力衰竭患者左心室功能  

Evaluation of left ventricular function in congestive heart failure by acoustic quantification

作　　者：徐冬梅 [1] 张梅 [2] 范崇伦 [3] 

机构地区：[1]济南市第三人民医院心内科 [2]250012,济南,山东大学齐鲁医院心内科 [3]济南市中心医院呼吸内科

出　　处：《中华医学超声杂志（电子版）》2005年第4期222-223,共2页Chinese Journal of Medical Ultrasound(Electronic Edition)

摘　　要：目的探讨采用声学定量(AQ)技术观察充血性心力衰竭患者左心室功能的改变.方法对34例充血性心力衰竭患者(NYHA心功能Ⅲ～Ⅳ级),采用AQ技术测量左心室舒张末容积(EDV)、收缩末容积(ESV)、射血分数(EF)、峰值排空率(PER)、峰值快速充盈率(PRFR)、峰值心房充盈率(PAFR)及峰值快速充盈率与峰值心房充盈率之比(PRFR/PAFR),并与24例正常人的上述各参数测值进行对比分析.结果心衰组与正常组相比左心室EDV、ESV、PAFR及PRFR有不同程度的增大(P＜0.01或P＜0.05),EF和PER有不同程度的减低(P＜0.01或P＜0.05),而PRFR/PAFR差异无统计学意义.结论AQ技术有助于评价充血性心力衰竭患者的左心室收缩及舒张功能,对于晚期心衰患者左心室舒张功能的评价有一定局限性.Objective To evaluate the left ventricular systolic and diastolic function in patients with congestive heart failure （CHF） hy acoustic quantification （ AQ ）. Methods This series included 24 healthy subjects （control group） and 34 censecutive patients with CHF （NYHA functional class III to IV） who were diagnosed 13y physical examination, ECG, X-ray and echocardiography. Using AQ technique the left ventricle end diastolic volume （EDV） , end systolic volume （ESV） , ejection fraction （EF） , peak ejection rate （PER）, peak rapid filling rate （PRFR） and peak atrium filling rate （PAFR） were measured; and the PRFR/PAFR ratio was calculated. All these parameters were comparatively analyzed with those in control group. Results Compared with healthy controls, EDV, ESV, PRFR and PAFR significantly increased （ P 〈 0.01 or P 〈 0.05） ; EF and PER significantly decreased （ P 〈 0. 01 or P 〈 0.05 ） ; while PRFR/PAFR ratio had no significant differences. Conclusions AQ is helpful to evaluation of left ventricular systolic and diastolic function in CHF patients; while for evaluation of left ventricular diastolic function of heart failure patients at late phase, AQ is limited.

关 键 词：超声心动描记术 充血性心力衰竭 左心室功能 声学定量 充血性心力衰竭患者 声学定量技术评价 左心室舒张功能 左心室收缩 不同程度 心衰患者 

分 类 号：R259.416.1[医药卫生—中西医结合] R581.1[医药卫生—中医内科学]