颅内钙化的MRI多序列研究  

MRI features of intracranial calcification

作　　者：吴永峻[1] 陈武标[1] 田国强[1] 

机构地区：[1]广东医学院附属医院放射科MRI室,广东湛江524001

出　　处：《广东医学院学报》2005年第4期368-369,372,共3页Journal of Guangdong Medical College

摘　　要：目的:探讨颅内钙化的MRI的SE-T1WI、FSE-T2WI、GRE-T2*WI信号改变和三种序列对钙化病灶的检出敏感性.方法:收集33例颅内钙化CT和MRI资料,钙化病灶共45处,均进行SE-T1WI、FSE-T2WI、GRE-T2*WI(TE为30ms)扫描,15例共27处钙化病灶行第2次GRE-T2*WI扫描(TE为50ms).结果:(1)SE-T1WI、FSE-T2WI、GRE-T2*WI对钙化的检出敏感性分别为64.4%、84.4%、91.1%;(2)MRI检出率与钙化病灶的部位、大小有关, '中心性'病灶的检出率高于'偏中心'病灶(GRE-T2*WI除外)(P＜0.01);GRE -T2*WI对'偏中心性'的钙化病灶检出高于SE-T1WI序列;大病灶的检出率明显高于小病灶(P＜0.05～0.01).(3)MRI的三种序列均可显示为高、等、低、极低等4种信号,SE-T1WI以等和低信号多见,FSE-T2WI、GRE-T2*WI以低、极低信号多见.(4)GRE-T2*WI序列延长TE时间,钙化病灶的磁敏感性不增强,可以与铁沉积疾病鉴别.结论:颅内钙化的MRI信号多变,与钙化病灶的部位、大小有关,GRE-T2*WI序列对钙化灶的检出具有明显价值.Objective： To observe MRI characteristics of intracranial calcification （IC）. Methods： CT and MRI data of 33 patients with IC were analyzed. Results： The sensitivity of SE-T1WI, FSE-T2WI and GRE -T2^＊WI for detecting IC was 64.4%, 84.4%, and 91.1%, respectively, and its sensitivity was related to the location and size of lesions. There existed hyper-, iso-, hypo-, and very low signal intensities on 3 images. Iso- and hypo- intensities were often seen on SE-T1WI, but hypo- and very low intensities occurred on FSE-T2WI and GRE-T2^＊WI. Magnetic susceptibility showed no intensification on GRE-T2^＊WI with the prolongation of TE time, which was different from iron deposition. Conclusion： The signal intensities of intracranial calcification are variable, and are related to its location and size. GRE-T2^＊WI is applicable to the detection of intracranial calcification.

关 键 词：钙质沉着症 脑疾病 磁共振成像 体层摄影术 X线计算机 

分 类 号：R682.11[医药卫生—骨科学] R816.1[医药卫生—外科学]