工作场所空气中庚醛的测定方法研究  

A study on the determination method of heptanal in workplace

作　　者：张志虎[1] 邵华[1] 冯斌[1] 

机构地区：[1]山东省职业卫生与职业病防治研究院,济南250062

出　　处：《中国卫生检验杂志》2005年第9期1035-1036,共2页Chinese Journal of Health Laboratory Technology

基　　金：山东省自然科学基金资助项目(Y2002C30)

摘　　要：目的:建立一种实用的工作场所空气中庚醛的采样、测定方法.方法:用浸渍2,4-二硝基苯肼(DNPH)的硅胶管采样,用乙腈在超声中洗脱,高效液相色谱分离,二极管阵列检测器检测.结果:方法简便、准确、灵敏度高.标准曲线的相关系数0.9999,加标回收率 96.68%～100.76%,相对标准偏差 0.33%～0.46%,采样效率 100%.结论:本方法各项指标均达到<工作场所空气中毒物检测方法的研制规范>的要求,能准确地测定空气中庚醛.Objective：To establish a useful method for sampling and detection of heptanal in workplace. Methods：Glass tubes filled with DNPH - coated silica gel were used for air sampling. The DNPH - derivatives were extracted from the silica gel by ultrasonic treatment with acetonitrile. Analysis of the DNPH - derivatives was carried out using a HPLC with diodenarray （ UV/ DAD） detection. Results：The mehtod was simple, accurate, and highly sensitive. The Correlation coefficient of calibration curves was 0. 99994. Recovery rates of 96. 68% - 100. 76% were determined. The relative standard deviation 0. 33% -0. 46% and sam- piing efficiency 100% were obtained. Conclusion：This method is conformed with the requirements of “Standardization of methods for determination of toxic substance in workplace”. Heptanal in air could be determined accuratly.

关 键 词：庚醛 检测 高效液相色谱法 工作场所 

分 类 号：R134.4[医药卫生—劳动卫生]