骨基质明胶诱导成骨活性的实验研究  

Experimental Study on the Osteoinductive Property of Bone Matrix Gelatin

作　　者：宋知非[1] 佘丹阳[1] 李承球[1] 杨秀珍[1] 陈新[1] 

机构地区：[1]南京大学医学院附属鼓楼医院,210008

出　　处：《江苏医药》1996年第1期6-8,共3页Jiangsu Medical Journal

摘　　要：实验将同种骨基质明胶（BMG）和脱钙骨基质DBM分别植入大鼠肌肉，以评价BMG的诱导成骨活性。术后2～20天X线摄片和光镜观察的结果显示，BMG骨诱导能力明显优于DBM。作者探讨了肌内诱导成骨的发生机制，BMG骨诱导能力较强的原因和新骨形成伴随有植入物吸收的意义。All1ogenic bone matrix gelatin(BMG) and decalcified bone.matrix(DBM) were separately implantedinto the rat muscles to evaluate the osteoinductive property of BMG. The results of radiographic examinations andlight mcroscopic observations 20 days after implantation showed that the capacity of inductive osteogenesis ofBMG was significantly superior to that of DBM. The possible mechanism of osteoinduction in muscles,relating tothe cause of better bone induction capacity of BMG,and importance of resorption of the implanted materials accom-panying new bone formation were discussed.

关 键 词：骨基质明胶 骨诱导 成骨活性 

分 类 号：R318.08[医药卫生—生物医学工程] R687.34[医药卫生—基础医学]