糖尿病视网膜病变中医证候与西医分期的关系研究  

Relationship Between TCM Syndrome Patterns and Western Medical Staging in Diabetic Retinopathy

作　　者：易细香[1] 余杨桂[2] 李景恒[2] 詹宇坚[2] 黄仲委[2] 王舜杏[2] 李志英[2] 

机构地区：[1]北京大学深圳医院眼科,广东深圳518036 [2]广州中医药大学第一附属医院眼科,广州510405

出　　处：《广州中医药大学学报》2005年第5期362-365,共4页Journal of Guangzhou University of Traditional Chinese Medicine

摘　　要：[目的]研究糖尿痛视网膜病变患者中医证候演变特征。[方法]对245例糖尿病视网膜病变患者不同分期的中医证候进行分析。[结果]经计数资料的相关分析表明,糖尿病视网膜病变的中医证候及其合并证候与病变的分期和病程均存在相关性(均P=0.0000)。①气阴两虚证、阴虚内热证、脾虚湿热证在亚临床期、单纯期分别占33.85%、33.00%、32.30%、25.00%、21.54%、26.00%;与同期脾虚痰湿证、阴阳两虚证相比较,差异有统计学意义(P<0.05或P< 0.01);在增殖期,气阴两虚证、脾虚痰湿证、阴阳两虚证分别占39.74%、26.92%、19.23%,与阴虚内热证、脾虚湿热证相比较,差异均有统计学意义(P<0.05),阴阳两虚证在增殖期所占比例与单纯期、亚临床期比较,差异均有统计学意义(P<0.05);②病程在5年以下者,气虚证占85.48%为最多见,其次是阴虚证;病程在15年以上者,血瘀证型、痰湿证型达100%。[结论]糖尿病视网膜病变的中医证候在各期、各病程阶段是动态变化的。[Objective] To study the progression of TCM syndrome patterns in diabetic retinopathy （DR）. [Methods] TCM syndrome patterns of 245 DR patients in different stages were analyzed. [ Results] The study showed that TCM syndrome patterns and its complicated syndromes have a correlation with pathological stages and disease courses. （1） The percentage of syndrome pattern of Qi- and yin- deficiency was 33.85% and 33.00%, yin deficiency with internal heat was 32.30% and 25.00%, and spleen deficiency with damp-heat was 21.54% and 26.00% in sub-clinical stage and simple stage, respectively. The difference was significant as compared with the patterns of spleen deficiency with phlegmdamp, yin- and yang- deficiency （P 〈 0.05 or P 〈 0.01 ）. Tile percentage of Qi- and yin- deficiency, spleen deficiency with phlegm-damp, and yin- and yang- deficiency was 39.74%, 26.92% and 19.23% in the proliferative stage, respectively. The difference was significant as compared with the patterns of yin deficiency with internal heat, and spleen deficiency with damp-heat （ P 〈 0.05）. The percentage of yin- and yang- deficiency in proliferative stage differed from that in simple stage and sub-clinical stage （P 〈0.05）. （2） In the cases with disease course shorter than 15 years, Qi deficiency pattern accounted for 85.48 %, having the highest percentage, and the percentage of yin deficiency pattern came the next. In the cases with disease course longer than 15 years, the patterns of blood stasis, and phlegm-damp accounted for 100%. [Conclusion] TCM syndrome patterns of DR vary with westem medical staging and disease

关 键 词：糖尿病/并发症 视网膜变性/中医病机 

分 类 号：R774.13[医药卫生—眼科]