^(99m)Tc-EHIDA肝胆显像和十二指肠引流液胆红素测定对婴儿黄疸的鉴别诊断  

Differentiation of infantile jaundice with^(99m)Tc-EHIDA hepatobiliary scintigraphy and determination of bilixanthine from duode- nal drainage

作　　者：赵明[1] 吴华[1] 黄志华[2] 鲜于志群[1] 胡健[1] 周健[1] 周显英[1] 罗茂来[1] 赖世英[1] 田大武 

机构地区：[1]同济医科大学附属同济医院核医学科,武汉430030 [2]同济医科大学附属同济医院核儿科,武汉430030

出　　处：《中华核医学杂志》1996年第1期41-43,共3页Chinese Journal of Nuclear Medicine

摘　　要：核素肝胆显像结合十二指肠引流液胆红素含量测定,为婴儿黄疸提供更有效的鉴别诊断方法。33例婴儿黄疸患儿均经手术、术中肝活检及临床随访证实,行(99m)~Tc-亚氨基二乙酸(EHIDA)肝胆显像和十二指肠引流液胆红素含量测定。(99m)~Tc-EHIDA 肝胆显像诊断胆道闭锁的敏感性为100%,特异性为72.7%。十二指肠引流液胆红素含量测定则分别为100%和94.45%。核素肝胆显像方法灵敏、简单、安全、无创伤,对肠道不显影患儿再行十二指肠引流液胆红素含量测定,可提高诊断的特异性。PURPOSE The purpose of this study was to develop an effective diagnostic method for infantile jaundice.METH- ODS ^(99m)Tc-EHIDA hepatobiliary scintigraphy and determination of bilixanthine from duodenal drainage were carried out in 33 in- fants with persistent jaundice.The final diagnosis was confirmed by surgical operation,pathology or clinical follow-up.RESULTS For diagnosing biliary atresia,the sensitivity and specificity of scintigraphy were 100% and 72.7% respectively and those of bilix- anthine measurement were 100% and 95.5%.CONCLUSIONS Hepatobiliary seintigraphy may he a sensitive,simple,safe and noninvasive method for differentiating infantile jaundice.Duodenal bilixanthine determination may improve the specificity in the case without intestinal radioactivity in scintigram.

关 键 词：新生儿黄疸 诊断 放射性核素 肝胆显像 胆红素 

分 类 号：R722.170.4[医药卫生—儿科]