强力咽喉饮提取工艺研究  

Study on the Extractive Process of Qiangliyanhou Mixture

作　　者：李国忠[1] 谢崇义[1] 吴杨[1] 

机构地区：[1]安徽省铜陵市人民医院药剂科,铜陵市244000

出　　处：《中国药房》2005年第17期1293-1295,共3页China Pharmacy

摘　　要：目的:优化强力咽喉饮的提取工艺。方法:分析处方药材所含成分的理化性质,确定以芳香水得量作为蒸馏工艺的考察指标;应用正交试验法,以水提取物中含固率和绿原酸含量为指标,考察加水量、煎煮前浸泡时间、煎煮时间和煎煮次数对提取效果的影响,筛选最佳配制工艺。结果:收集3倍药材量的蒸馏液为蒸馏工艺的最佳芳香水量;最佳水提工艺为煎煮前冷浸2h、加水总量为药材的15倍、煎煮3次、总煎煮时间为3h(每次1h)。结论:该工艺合理、可靠。OBJECTIVE： To optimize the technics for the extraction of Qiangliyanhou mixture. METHODS： The physico- chemical properties of the compositions in the formula medicinal substances were analyzed, the obtained quantity of aqua aromatica was used as an investigation index of distillation technics; The preparation technics was optimized by orthogonal experiment in which the extraction ratio of the water extractives and the content of chlorogenic acid were used as the indexes to investigate the influence of the amount of water added, the soaking time before decoction, decoction time and times of decoction on the extraction result. RESULTS： The optimized amount of aqua aromatica in the distillation procedures was collecting distillate that is 3 times the amount of the medicinal substances; The optimum water extraction condition was： the medicinal substances was soaked for 2 hours by adding 15 times amount of water before decocting for total 3 hours （3 times×1 hour / time）. CONCLUSION： The preparation procedure is reasonable and reliable.

关 键 词：强力咽喉饮 芳香水 正交设计 含固率 绿原酸 

分 类 号：R284.2[医药卫生—中药学]