N20-P25、N18消失在深昏迷预后判断中的价值  

Predictive value of potentials N20-P25 and N18 in deep comatose patients

作　　者：罗本燕[1] 唐敏[1] 张玲菊[1] 王建琴[1] 夏一青[1] 李舜伟[2] 

机构地区：[1]浙江大学医学院附属第一医院神经内科,杭州310003 [2]中国医学科学院中国协和医科大学北京协和医院神经内科

出　　处：《中华神经科杂志》2005年第8期488-490,共3页Chinese Journal of Neurology

基　　金：浙江省科技厅资助项目(2004C33027)

摘　　要：目的评价短潜伏期体感诱发电位(shortlatencysomatosensoryevokedpotentials,SLSEP)N20P25、N18消失在深昏迷患者预后判断中的作用。方法运用便携式诱发电位仪,对95例深昏迷患者进行SLSEP检测,记录脑皮质电位N20P25和周围电位N13,44例患者同时记录脑皮质下电位N18。结果95例患者N20P25均消失(100%),8例患者因有周围神经损伤未记录到周围电位N13;44例患者中脑皮质下电位N18消失者38例(86.4%)。结论95例患者SLSEP检查结果与临床判断完全吻合。在脑功能判断中,N20P25敏感性较高,N18特异性较高,二者均消失高度提示脑功能预后不良。Objective To evaluate the value of short latency somatosensory evoked potentials （SLSEP） in prediction of the outcome in deep comatose patients. Methods SLSEP were examined by portable evoked potentials machine in 95 patients. N13 and N20-P25 potentials were recorded in all of the cases. At the same time, 44 of them had a record of N18 potential. The clinical examination included those levels of consciousness, reflexes of brain stem and apnea tesL Results All 95 cases had achieved the clinical standard of brain death and lost N20-P25 potentials. N13 potential existed and N20-P25 potential disappeared in 87 cases （91.6%）, and N18 potential disappeared in 38 of 44 cases （86.4%） . Conclusion N20-P25 potentials should have a high sensitivity and N18 potential a high specificity. It suggests that there appear a severe outcome when they both disappear.

关 键 词：诱发电位 躯体感觉 昏迷 预后判断 N18 短潜伏期体感诱发电位 深昏迷 周围神经损伤 昏迷患者 脑功能判断 价值 

分 类 号：R449[医药卫生—诊断学]