三种方法治疗早期梅毒的疗效比较研究  

Study on the Clinical Therapeutic Effective of Three Methods in Patients with Early Congenital Syphilis

作　　者：乔国安[1] 历志[1] 刘丽红[1] 

机构地区：[1]哈尔滨市第三医院,哈尔滨150060

出　　处：《中国性科学》2005年第4期11-12,共2页Chinese Journal of Human Sexuality

摘　　要：目的:研究三种方法治疗早期梅毒的疗效。方法:将近二年的118例早期梅毒患者随机分成三组,第一组采用苄星青霉素肌注,第二组采用头孢曲松静点+苄星青霉素肌注,第三组采用阿奇霉素静点+口服。结果:三种方法均具有较好效果,但疗效比较差异有显著性(P<0.05),头孢曲松+苄星青霉素组平均有效时间最短,治愈率最高达94.6%。结论:为尽快治愈早期梅毒,应选择敏感、高效的抗生素,头孢曲松及苄星青霉素为首选,青霉素过敏者可选用阿奇霉素治疗。Objectives： To study the clinical therapeutic effective of three methods in the patients with early congenital syphilis. Methods：118 patients with early congenital syphilis of late two years were divided randomly into three groups：The first group were treated with Bicillin by I.M.The second group were treated with Ceftriaxone by venous inflow and Bicillin by intramuscular.The third group were treated with Azithromycin by venous inflow and poros.Result：The three methods all had good efficacy .But there were differences in all groups （P〈0.05）.The Ceftriaxone and Bicillin group had the shortest average efficacy time.The cure rate was 94.6%. Conclusion： For curing early congenital syphilis,we must select sensitive and high-performance antibioti,Ceftriaxone and Bicillin were initial selection.Penicillin allergic constitution can select Azithtomycin .

关 键 词：早期梅毒 苄星青霉素 头孢曲松 阿奇霉素 疗效比较研究 素治疗 青霉素肌注 梅毒患者 有效时间 显著性 

分 类 号：R969.4[医药卫生—药理学] R759.11[医药卫生—药学]