荧光分光光度法测定盐酸洛美沙星胶囊含量  

Determination of lomefloxacin hydrochloride in capsule by spectrofluorometry

作　　者：冯琳[1] 储秋萍[1] 邵志高[1] 

机构地区：[1]江苏省人民医院

出　　处：《中国抗生素杂志》1996年第1期17-19,共3页Chinese Journal of Antibiotics

摘　　要：采用荧光分光光度法测定洛美沙星胶囊的含量。激发／发射波长为２８７／４５５ｎｍ，平均回收率为９８．０％，ＲＳＤ为０．９８％。在０．１～１．０μｇ／ｍｌ范围内，其荧光强度与浓度线性关系良好。Lomefloxacin is a new antimicrobial agent of quinolones. The content of lomefloxacin hydrochloride in capsule was determined by spectrofluorometry. The excitation and emission wavelength were 287 and 455nm respectively. The average recovery was 98.0%, RSD 0. 98%. The relationship of fluorescence and concentration was linear in 0. 1～1. 0μg/ml for lomefloxacin hydrochloride.

关 键 词：洛美沙星 胶囊剂 荧光分光光度法 

分 类 号：R978.19[医药卫生—药品]