2种席夫碱钼(VI)配合物与大肠杆菌作用的微量热研究  

Microcalorimetric Study of the Action of Two Kinds of Schiff Bases Mo(VI) Complexes on Growth Metabolism of Escherichia coli

作　　者：朱立红[1] 许名飞[2] 叶发兵[1] 莫小曼[1] 祝心德[2] 

机构地区：[1]黄冈师范学院化学系,湖北黄冈438000 [2]华中师范大学化学系,湖北武汉430079

出　　处：《安徽农业科学》2005年第8期1456-1457,共2页Journal of Anhui Agricultural Sciences

基　　金：湖北省教育厅重点项目(98A069)资助。

摘　　要：用LKB!2277生物活性检测系统测定了新合成的席夫碱钼(VI)配合物MoO(2PT)2和MoO(2NPT)2在37℃时对大肠杆菌作用的产热曲线;根据产热曲线求算了在席夫碱钼(VI)配合物作用下,大肠杆菌生长代谢的速率常数k,抑制率I,传代时间G和半抑制浓度IC50等热力学参数。结果表明,席夫碱钼(VI)配合物对大肠杆菌有抑制作用。The bio-thermo-chemical characteristics of the actions of two kinds of schiff bases Mo（VI ） Complexes MoO2（PT）2 and MoO2（NPT）2 on growth metabolism of Escherichia coil were studied by means of a LKB-2277 bioactivity monitor at 37℃. The maximum power, Pmax; the growth rate constant, k; inhibitive ratio I （%） and half inhibition concentration IC50 （mg/L）, respectively, had been obtained, The experimental results showed that the schiff base Mo（VI ）complexes possessed the anti-bacterium activities.

关 键 词：席夫碱 钼(VI)配合物 微量热学 大肠杆菌 

分 类 号：O642.3[理学—物理化学]