尿素醇解法制氨基甲酸甲酯体系的反相高效液相色谱分析  

Analysis of the synthesis of methyl carbamate from urea and methanol by reversed phase high performance liquid chromatography

作　　者：茆福林[1] 吴廷华[1] 戴春华[2] 郑卓群[1] 张奇能[1] 陈飞[1] 

机构地区：[1]浙江师范大学物理化学研究所,金华321004 [2]盐城师范学院化学系,盐城224002

出　　处：《分析试验室》2005年第8期85-87,共3页Chinese Journal of Analysis Laboratory

基　　金：浙江省科技厅(2004C31053);浙江丰登化工股份有限公司资助

摘　　要：采用反相高效液相色谱法,在两根串联的C18柱上以甲醇-水为流动相,在8min内将尿素和氨基甲酸甲酯进行分离,在215 nm波长下检测.在甲醇溶液中的质量浓度0～16%和0～50%范围内其峰面积和质量浓度呈良好的线性关系,线性回归方程分别为AUrea=148565x-39384,R2=0.9995;AMC=69055x90493,R2=0.9985.Separation and determination of urea and methyl carbamate by reversed phase high performance liquid chromatography was performed within 8 minutes on a dual calunm system, using methanol-water as a mobile phase at a wavelength of 215 nm. A linear relationship between mass concentration and peak area was obtained over the range 0- 16% with a correlation coefficient of 0.9995 for urea and 0 -50% with a correlation coefficient of 0.9985 for methyl carbamate.

关 键 词：反相高效液相色谱 尿素 氨基甲酸甲酯 

分 类 号：O658.1[理学—分析化学]