狼疮丸治疗SLE的临床与实验研究  

Clinical and Laboratorial Study of the Effect of Antilupus Pill on Systemic Lupus Erythematosus

作　　者：王仲英[1] 

机构地区：[1]白求恩医科大学第三临床学院内二科

出　　处：《中西医结合杂志》1989年第8期465-468,452,共4页

摘　　要：采用清热解毒为主、辅以凉血祛风和活血化瘀的狼疮丸治疗 SLE306例,临床证实,总有效率达85.0%。该药对身体无副作用,对部份患者可用狼疮丸代替激素的维持量。药理证明,该药对不同原因引起的炎症,包括Ⅰ、Ⅲ、Ⅳ型变态反盧,均有抑制作用。但对免疫反应的致敏期和反应期均无作用。本文还就狼疮丸作用机理、SLE 的中西医结合治疗等进行了探讨。An effort was made to get a clear understanding of antilupus pill(ALP)action on systemic lupus erythematosus(SLE)and to evaluate its therapeutic effect.ALP was originated from a notable efficacious recipe by an expert physician of TCM.It was prepared with the decoction of 17 Chinese medical herbs(such as Flos Lonicerae,Salvia miltiorrhiza etc.)to dispell noxious heat from blood, replenish the vital essence,invigorate blood circulation and resolve the stagnation.The effective rate of 92% for 230 SLE patients treated with ALP and corticosteroids,85% for 76 patients treated with ALP alone,79～89% for rash,trichomadesis,oral or nasal pharynx ulcer patients,and arthritis patients without deformation were obtained The ANA titer was decreased markedly for 75% patients.ALP had no side effect and could take the part place of hormone in dosage and lessen its side effect.Through pharmacological verification it was concluded that ALP could inhibit the inflammatory process from various causes including type Ⅰ,Ⅲ and Ⅳ hypersensitivity,and show no response on both sensitizing and reactive stages of immunological reaction.

关 键 词：狼疮丸 红斑狼疮 硬皮病 脂膜炎 

分 类 号：R593.3[医药卫生—内科学]