鼻脑型毛霉菌病颅内感染误诊1例并文献复习  

Misdiagnosis of Intracranial Infection Caused by Rhinocerebral Mucormycosis:1 Case Report and Literature Eeview

作　　者：黄金生[1] 王晓亮[1] 林荫[1] 

机构地区：[1]福建省南平市第一医院神经外科,353000

出　　处：《中国误诊学杂志》2005年第11期2015-2017,共3页Chinese Journal of Misdiagnostics

摘　　要：目的:阐明鼻脑型毛霉菌病(RhinocerebralMucormycosis,RCM)发病的危险因素、误诊原因、临床诊治等要点,以期提高对本病的认识。方法:报告1例头面部外伤后鼻脑型毛霉菌颅内感染死亡病例,并结合文献探讨该病的易感因素、临床特点、诊断治疗方法。结果:对毛霉病的认识不足、原发糖尿病误认为脑外伤所致、病原学检查不及时是延误诊断治疗的主要原因。结论:早期诊断、治疗,使用二性霉素B、及时有效地控制血糖和积极彻底的外科清创手术、高压氧治疗是降低病死率积极有效的方法。Objective： To clarify the risk factor, misdiagnostic reason, clinical characteristics and treatment of rhinocerebral mucormycosis,in order to improve recognition of the disease. Methods：One case of intracranial infection caused by RCM with traumatopathy of head with death was reported and the predisposing factors,cllnical characteristics, diagnosis and therapy of RCM were discussed and the relevant literature was reviewed. Results ：The major reason of misdiagnosis included lack of recognition of RCM ,misdiagnsis of diabetes mellitus as cerebral trauma, and delayed etiological examination. Conclusions ：Prompt diagnosis, application of amphoterricin B,control of hyperglycemia and acidosis,surgical debridement and hyperbaric oxygen treatment are effective measure of decreasing case fatality.

关 键 词：毛霉菌病/诊断 脑膜炎 真菌性/诊断 误诊 

分 类 号：R519.904[医药卫生—内科学]