双波长比值光谱法测定复方益康宁片二组分的含量  

Dual-wavelength ratio spectrophotometry for determination of procaine hydroc hloride and vitamin B_6 in compound Yikangning tablets

作　　者：黄喜茹[1] 刘伟娜[1] 周亚君[1] 曹冬[1] 

机构地区：[1]河北医科大学药学院分析化学教研室,河北石家庄050017

出　　处：《第四军医大学学报》2005年第17期1601-1603,共3页Journal of the Fourth Military Medical University

摘　　要：目的:建立复方益康宁片中盐酸普鲁卡因和维生素B6的双波长比值光谱测定法. 方法:绘制盐酸普鲁卡因和维生素B6的比值光谱,选择其峰点或谷点作为测定波长对有效地消除共存组分的干扰,以实现对被测组分的准确测定. 结果:在选定的实验条件下,盐酸普鲁卡因和维生素B6在5.0～50.0 mg/L范围线性关系良好,平均回收率分别为99.5%, 98.3%和相对标准偏差(RSD)分别为1.2%, 0.8%. 结论:该方法简便、快速、重现性好,结果满意.AIM ： To establish dual - wavelength ratio spectrophotometry for determination of procaine hydrochloride and vitamin B, in compound Yikangning tablets. METHODS ： The ratio spectra was determined and the wavelength pair were selected at the peak point or valley point of ratio spectra , to eliminate the interference of other components. RESULTS： Linearity between the absorbance and concentration of procaine hydrochloride and vitamin B6 was obtained in the range of 5.0 - 50.0 mg/L under the optimum conditions. The average recoveries and relative standard deviations（RSD） of procaine hydrochloride and vitamin B, were 99. 5%, 1. 2% and 98. 3%, 0. 8%, respectively. CONCLUSION： The method was simple , rapid and reproducible , the interference of two components on each other may be eliminated and the results were satisfactory.

关 键 词：双波长比值光谱法 盐酸普鲁卡因 维生素B6 复方益康宁 

分 类 号：R927[医药卫生—药学]