A Facile Synthesis of 2, 7-Diaminothieno[2, 3-d:5,4-d]-dipyrimidine-4, 5(3H, 6H)diones  

作　　者：Sheng Zhen XU Min Hui CAO Ming Wu DING Hong Wu HE 

机构地区：[1]Key Laboratory of Pesticide ＆ Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079

出　　处：《Chinese Chemical Letters》2005年第9期1177-1180,共4页中国化学快报（英文版）

基　　金：We gratefully acknowledge financial support of this work by the National Key Project for Basic Research(2003CB114400,2003CB114406);the National Natural Science Foundation of China(Project No.20372023 and 20102001).

摘　　要：2, 7-Diaminothieno[2, 3-d：5, 4-d]dipyrimidine-4, 5（3H, 6H）diones 4 were synthesized by a facile synthetic method, which includes bis-aza-Wittig reaction of bis-iminophosphorane 1 with aromatic isocyanate to give bis-carbodiimide 2 and subsequent reaction of 2 with various dialkylamine in the presence of solid K2CO3 or EtONa.2, 7-Diaminothieno[2, 3-d：5, 4-d]dipyrimidine-4, 5（3H, 6H）diones 4 were synthesized by a facile synthetic method, which includes bis-aza-Wittig reaction of bis-iminophosphorane 1 with aromatic isocyanate to give bis-carbodiimide 2 and subsequent reaction of 2 with various dialkylamine in the presence of solid K2CO3 or EtONa.

关 键 词：Thieno[2 3-d：5 4-d]dipyrimidine-4 5（3H 6H）dione bis-aza-Wittig reaction bisimino-phosphorane bis-carbodiimide synthesis. 

分 类 号：O623.624[理学—有机化学]