DCCP and DICP: Construction and Analyses of Databases for Copper-and Iron-Chelating Proteins  

作　　者：Hao Wu Yan Yang Sheng-Juan Jiang Ling-Ling Chen Hai-Xia Gao Qing-Shan Fu Feng Li Bin-Guang Ma Hong-Yu Zhang 

机构地区：[1]Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Shandong University ofTechnology, Zibo 255049, China [2]Isotope Research Laboratory, Sichuan Agriculture University, Yaan 625014,China [3]College of Life Sciences, Shandong Normal University, Jinan 250014, China.

出　　处：《Genomics, Proteomics & Bioinformatics》2005年第1期52-57,共6页基因组蛋白质组与生物信息学报（英文版）

基　　金：This work was supported by the National Basic Research Program of China(2003CB114400);the National Natural Science Foundation of China(Grant No.30100035).

摘　　要：Copper and iron play important roles in a variety of biological processes, especially when being chelated with proteins. The proteins involved in the metal binding, transporting and metabolism have aroused much interest. To facilitate the study on this topic, we constructed two databases （DCCP and DICP） containing the known copper- and iron-chelating proteins~ which are freely available from the website http：//sdbi.sdut.edu.cn/en. Users can conveniently search and browse all of the entries in the databases. Based on the two databases, bioinformatic analyses were performed, which provided some novel insights into metalloproteins.Copper and iron play important roles in a variety of biological processes, especially when being chelated with proteins. The proteins involved in the metal binding, transporting and metabolism have aroused much interest. To facilitate the study on this topic, we constructed two databases （DCCP and DICP） containing the known copper- and iron-chelating proteins~ which are freely available from the website http：//sdbi.sdut.edu.cn/en. Users can conveniently search and browse all of the entries in the databases. Based on the two databases, bioinformatic analyses were performed, which provided some novel insights into metalloproteins.

关 键 词：copper and iron database primary sequence analysis secondary structure prediction SCOP classification 

分 类 号：Q58[生物学—生物化学]