可降解聚乳酸/羟基磷灰石杂化材料 Ⅰ.纳米羟基磷灰石的合成  

Degradable Poly Lactic Acid/Hydroxyapatite Hybrid Material Ⅰ.Preparation of Nano-hydroxyapatite

作　　者：王华林[1] 李延红[1] 史铁钧[1] 盛敏刚[1] 翟林峰[1] 王继植[1] 

机构地区：[1]合肥工业大学化工学院

出　　处：《应用化学》2005年第9期976-979,共4页Chinese Journal of Applied Chemistry

基　　金：安徽省自然科学基金资助项目(01044803)

摘　　要：基于化学共沉淀法,以正丁醇为表面处理剂,共沸蒸馏,制备出长径比约为2.5∶1.0柱纳米羟基磷灰石(HA),并对相关产物进行XRD、TEM、DSC、FT-IR的分析。结果表明,正丁醇与HA表面的OH基可以脱水形成C—O—P键,在HA表面接枝一层O—C4H9有机基团。HA经正丁醇表面处理后与未经表面处理的相比,晶化温度降低200℃左右,晶粒尺寸减小2/3左右,且团聚现象明显改善。N-Butyl alcohol was used as surface treatment agent to prepare columned nano-hydroxyapatite （HA） （L/D ratio is about 2.5/1 ） via azeotropic distillation based on chemical co-deposited method. The samples were characterized by XRD, TEM, DSC and FT-IR means, n-Butyl alcohol could dehydrate with the hydroxyl groups on the HA surface to form C-O-P bonds, so the -O-C4 H9 groups were grafted on HA particles. Compared with the untreated HA, the crystalline temperature of HA treated with n-butyl-alcohol was decreased by two hundred centigrade, the crystallite dimension of HA treated with n-butyl alcohol was reduced by two thirds, moreover, the particle aggregation phenomena was decreased obviously.

关 键 词：化学共沉淀 共沸蒸馏 纳米羟基磷灰石 表面处理剂 

分 类 号：O633[理学—高分子化学] R318[理学—化学]